Results 1 to 10 of about 15,094 (231)
Ophthalmology and Therapy, 2020 Background Creutzfeldt-Jakob disease (CJD) is a rare, fatal, neurodegenerative prion disease potentially transmissible through corneal transplantation.
Yasmyne Ronquillo +2 more
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CJD mimics and chameleons [PDF]
Practical Neurology, 2017 Rapidly progressive dementia mimicking Creutzfeldt–Jakob disease (CJD) is a relatively rare presentation but a rewarding one to become familiar with, as the potential diagnoses range from the universally fatal to the completely reversible.
S. Mead, P. Rudge
semanticscholar +4 more sources
Acquired prion disease: iatrogenic CJD, variant CJD, kuru. [PDF]
British Medical Bulletin, 2003 Human prion diseases can be classified as sporadic, hereditary or acquired. The cause of sporadic Creutzfeldt-Jakob disease (CJD) is unknown, hereditary cases are associated with mutations of the prion protein gene (PRNP) and acquired forms are caused by the transmission of infection from human to human or, as a zoonosis, from cattle to human. Although
R. Will
semanticscholar +3 more sources
CJD: Understanding Creutzfeldt-Jakob disease.
Nursing, 2016 Rare, transmissible, and rapidly progressive, Creutzfeldt-Jakob disease (CJD) is an ultimately fatal central nervous system infection caused by accumulation of abnormally shaped prion proteins in neurons (see Understanding prion proteins). Although categorized as an infection, CJD doesn't lead to the immune system or inflammatory response typical of ...
Vincent M. Vacca
semanticscholar +3 more sources
Acta Neuropathologica Communications, 2019 Current evidence indicating a role of the human prion protein (PrP) in amyloid-beta (Aβ) formation or a synergistic effect between Aβ and prion pathology remains controversial. Conflicting results also concern the frequency of the association between the
Marcello Rossi +8 more
doaj +2 more sources
Prion, 2014 It is now 18 years since the first identification of a case of vCJD in the UK. Since that time, there has been much speculation over how vCJD might impact human health.
Abigail B. Diack +7 more
semanticscholar +4 more sources
Canadian Creutzfeldt-Jakob disease incidence remained stable during the coronavirus disease (COVID-19) pandemic [PDF]
Frontiers in NeurologyIntroductionHealthcare disruptions imposed by the coronavirus disease (COVID-19) pandemic and possible biological links between SARS-CoV-2 and prion misfolding might influence the prevalence or characteristics of Creutzfeldt-Jakob Disease (CJD).
Jessy A. Slota +12 more
doaj +2 more sources
Is there a link between COVID-19 and Creutzfeldt-Jakob Disease? a Case Report [PDF]
Journal of Research in Clinical Medicine, 2021 Creutzfeldt-Jakob Disease (CJD) is a rare rapidly progressive neurodegenerative disease. The diagnosis of CJD is based on magnetic resonance imaging (MRI) findings, electro-encephalography (EEG), or 14-3-3 protein detection.
Ehsan Nasiri +3 more
doaj +1 more source
Validation and Application of Skin RT-QuIC to Patients in China with Probable CJD
Pathogens, 2021 The definite diagnosis of human sporadic Creutzfeldt–Jakob disease (sCJD) largely depends on postmortem neuropathology and PrPSc detection in the brain.
K. Xiao +5 more
semanticscholar +1 more source
Viruses, 2022 Background: CSF total-tau (t-tau) became a standard cerebrospinal fluid biomarker in Alzheimer’s disease (AD). In parallel, extremely elevated levels were observed in Creutzfeldt-Jakob disease (CJD).
Peter Hermann +6 more
doaj +1 more source