Results 41 to 50 of about 3,382,864 (170)

Basaloid Squamous Cell Carcinoma of the Head and Neck: Subclassification into Basal, Ductal, and Mixed Subtypes Based on Comparison of Clinico-pathologic Features and Expression of p53, Cyclin D1, Epidermal Growth Factor Receptor, p16, and Human Papillomavirus [PDF]

Journal of Pathology and Translational Medicine, 2017
Background Basaloid squamous cell carcinoma (BSCC) is a rare variant of squamous cell carcinoma with distinct pathologic characteristics. The histogenesis of BSCC is not fully understood, and the cancer has been suggested to originate from a totipotent ...
Kyung-Ja Cho, Se Un Jeong, Sung Bae Kim, Sang-wook Lee, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim   +6 more
doaj   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

CK19 and GPC3 expression in different histological variation of HCC.

, 2016
Thin trabecular HCC was usually accompanied by the pseudoglandular structure (blue arrow head). This histological variant mostly showed CK19−/GPC3− expression (A). Majority of SHCCs showed CK19+/GPC3+ expression. But nearly half of CK19+/GPC3+ cases with
Hui Xia (133168), Fudong Lv (3179163), Ruidong Zhu (3179169), Fang Cao (236777), Lu Yu (74016), Feng Chen (25347), Jiliang Feng (3179166), Shijie Zhang (119400), Chun Chang (415999), Guohua Zhu (73670), Lin Sun (105539)   +10 more
core   +1 more source

Diagnostic Value of TROP-2 and CK19 Expression in Papillary Thyroid Carcinoma in Both Surgical and Cytological Specimens

Clinical Pathology, 2019
Papillary thyroid carcinoma (PTC) represents the most common primary malignant thyroid tumor and its diagnosis is dependent on the presence of classic nuclear features that are sometimes seen in some non-neoplastic and benign lesions.
Asmaa Gaber Abdou, Mohammed Shabaan, Rania Abdallha, Nehal Nabil   +3 more
doaj   +1 more source

The Role of Immunohistochemistry in the Differential Diagnosis between Intrahepatic Cholangiocarcinoma, Hepatocellular Carcinoma and Liver Metastasis, as Well as Its Prognostic Value

Diagnostics, 2023
Intrahepatic cholangiocarcinoma (iCCA) is the second most frequent primary hepatic malignant tumor, after hepatocellular carcinoma (HCC). Its incidence has risen worldwide, yet the only potentially curative treatment, surgical resection, is seldom ...
Lavinia Patricia Mocan, Ioana Rusu, Carmen Stanca Melincovici, Bianca Adina Boșca, Tudor Mocan, Rareș Crăciun, Zeno Spârchez, Maria Iacobescu, Carmen Mihaela Mihu   +8 more
doaj   +1 more source

The Early Regenerative Events in the Human Tympanic Membrane After In Vivo Traumatization

The Laryngoscope, EarlyView.
At 20 h after in vivo traumatization a regenerative response in the human tympanic membrane is activated. The results show an upregulated proliferation activity in the UPT in early healing and confirm the previously described regenerative regions of the annulus and malleus.
Elnaz Sepehri, Cecilia Engmér Berglin, Yan Liu, Per Olof Eriksson, Magnus von Unge, Julia Arebro   +5 more
wiley   +1 more source

Immunohistochemical expression of PTCH1 and laminin in oral hyperplastic, premalignant, squamous cell carcinoma and recurrence Lesions samples [PDF]

, 2019
Objective: Laminin is a basal membrane glycoprotein that showed progressive loss of continuity from dysplasia to invasive carcinoma.The membranous receptor Patched (PTCH1) promotes the nuclear translocation and activation of the Gli family proteins ...
Kanar A. Hamaamin, Falah A. Hussein, Dena N. Mohammad   +2 more
core   +2 more sources

Inhibition of the Notch Signaling Pathway Reduces the Differentiation of Hepatic Progenitor Cells into Cholangiocytes in Biliary Atresia

Cellular Physiology and Biochemistry, 2018
Background/Aims: Viral infections, especially with rotavirus, are often considered an initiator of the pathogenesis of biliary atresia (BA). However, the mechanism by which rotavirus induces BA is still unclear.
Yongzhong Mao, Shaotao  Tang, Li Yang, Kang Li   +3 more
doaj   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Prognostic significance of CD44 and CK19 expression in head and neck squamous cell carcinoma

Южно-Российский онкологический журнал
Purpose of the study. To analyze and synthesize current scientific evidence on the role of CD44 and CK19 expression in the pathogenesis of head and neck squamous cell carcinoma (HNSCC), their diagnostic and prognostic significance, as well as their ...
Han Yuyao, S. I. Samoylova, I. V. Reshetov, Xu Shijun, D. N. Davidyuk, Yang Xinyi, P. T. Nwodo, N. S. Sukortseva, T. A. Demura   +8 more
doaj   +1 more source