Results 141 to 150 of about 55,554 (173)

5．CKD-MBD

Nihon Toseki Igakkai Zasshi
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CKD-MBD: an endless story

Journal of Nephrology, 2011
Renal failure is a growing problem that involves a large part of the population and has a great social impact, with often incapacitating complications, mainly related to mineral bone disorders (MBD) and cardiovascular diseases. Analysis of the recent scientific literature confirms that a large number of chronic kidney disease (CKD) patients develop an ...
D. Brancaccio, M.G. Cozzolino
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[CKD-MBD in Peritoneal Dialysis].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2018
CKD-MBD is a systemic disorder of the mineral and bone metabolism as a result of CKD. The clinical relevance of this syndrome has led to the identification of the biochemical targets to be achieved in order to improve the outcome of the patient.
Rocca, Anna Rachele, Gnerre Musto, Tania, Mazzaferro, Sandro   +2 more
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CKD-MBD: from the Pathogenesis to the Identification and Development of Potential Novel Therapeutic Targets

Current Osteoporosis Reports, 2018
Purpose of Review: Although we have seen tremendous advances in the comprehension of CKD-MBD pathophysiology during the last few years, this was not accompanied by a significant change in mortality rate and quality of life.
Rosilene M Elias, Maria Aparecida Dalboni, Rosa M A Moysés   +2 more
exaly   +2 more sources

New scenarios in secondary hyperparathyroidism: etelcalcetide. Position paper of working group on CKD-MBD of the Italian Society of Nephrology [PDF]

Journal of Nephrology, 2019
Bone mineral abnormalities (defined as Chronic Kidney Disease Mineral Bone Disorder; CKD-MBD) are prevalent and associated with a substantial risk burden and poor prognosis in CKD population.
Antonio Bellasi, Mario Cozzolino, Fabio Malberti   +2 more
exaly   +4 more sources

Bone evaluation in paediatric chronic kidney disease: clinical practice points from the European Society for Paediatric Nephrology CKD-MBD and Dialysis working groups and CKD-MBD working group of the ERA-EDTA

Nephrology Dialysis Transplantation, 2021
Mineral and bone disorder (MBD) is widely prevalent in children with chronic kidney disease (CKD) and is associated with significant morbidity. CKD may cause disturbances in bone remodelling/modelling, which are more pronounced in the growing skeleton ...
Sevcan A Bakkaloglu, Justine Bacchetta, Maren Leifheit-Nestler   +2 more
exaly   +2 more sources

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CKD-MBD as a systemic disorder

Bone, 2009
The kidney is one of themost important organs in the regulation of mineral metabolism [1]. In patients with chronic kidney disease (CKD), abnormalities in mineral metabolism inevitably develop without appropriate management. The biochemical abnormalities result from disturbances in calcium, phosphate, PTH, FGF-23, and vitamin D metabolism [2].
Masafumi, Fukagawa, Tilman B, Drüeke
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Sclerostin and CKD-MBD

Current Osteoporosis Reports, 2015
Declining kidney function is associated with sequential systemic changes in mineral homeostasis leading to pathologic alterations in the cardiovascular system and the skeleton. One of the earliest changes in response to renal injury is the increased osteocyte production of secreted factors including the anti-anabolic protein, sclerostin.
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Sclerostin: a new biomarker of CKD–MBD

International Urology and Nephrology, 2019
The causes of the increased cardiovascular risk associated with kidney diseases partly reside in the chronic kidney disease-mineral bone disorder (CKD-MBD) syndrome. Three cardiovascular risk factors [hyperphosphatemia, vascular calcification, and elevated fibroblast growth factor 23 (FGF23)] levels have been discovered within the CKD-MBD over the last
Andreja Figurek, Merita Rroji, Goce Spasovski   +2 more
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