Results 51 to 60 of about 1,152,205 (156)

Association of neutrophil/high-density lipoprotein cholesterol ratio with the cardiovascular-kidney-metabolic syndrome and its cardiovascular mortality

Frontiers in Nutrition
BackgroundCardiovascular-kidney-metabolic (CKM) syndrome is a novel multi-system disease defined by the American Heart Association (AHA). This study aims to investigate the associations between the neutrophil/high-density lipoprotein cholesterol ratio ...
Yaying Xu
doaj   +1 more source

Cardiovascular–Kidney–Metabolic Overlaps, Clinical Outcomes, and Medications Among Patients With Heart Failure: Results From the Chinese Cardiovascular Association Database–Heart Failure Center Registry

MedComm, Volume 7, Issue 10, October 2026.
In a nationwide heart failure cohort, cardiovascular–kidney–metabolic (CKM) multimorbidity was common in Chinese hospitalized heart failure (HF) patients and associated with poor prognosis. Higher CKM burden and combinations identified high‐risk patients.
Xiang Wang, Jingkuo Li, Yi Li, Lubi Lei, Wei Wang, Xuyang Meng, Chenxi Xia, Chenguang Yang, Lihua Zhang, Yuhua Liao, Weimin Li, Yugang Dong, Xinli Li, Jingmin Zhou, Jiefu Yang, Fang Wang   +15 more
wiley   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Real‐World Use of Semaglutide for Weight Management: Dose Titration, Discontinuation Patterns and Weight Changes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8905-8912, October 2026.
ABSTRACT Aim In December 2022, semaglutide injections for weight management were marketed in Denmark. Pre‐marketing trials documented high efficacy when adherence to the treatment and the recommended dose titration schedule was followed. This study aimed to describe real‐world use of semaglutide, including dose titration, discontinuation patterns and ...
Mie Dyberg Skandov, Katrine McLain Christensen, Dagmar Abelone Dalin, Janne Unkerskov, Andreas Brønden, Marie Lund, Mikkel Bring Christensen, Kristian Karstoft   +7 more
wiley   +1 more source

Serum uric acid is associated with advanced stages in patients with cardiovascular-kidney-metabolic syndrome

Journal of Cardiothoracic Surgery
Background In 2023, the American Heart Association introduced the cardiovascular-kidney-metabolic (CKM) syndrome to comprehensively assess multimorbidity involving obesity, diabetes, chronic kidney disease, and cardiovascular disease. This study aimed to
Dingyuan Tu, Yutang Li, Yujuan Wang, Jianming Wang   +3 more
doaj   +1 more source

Association between the life’s essential 8 health behaviors score and all-cause mortality in cardiovascular-kidney-metabolic syndrome patients

Frontiers in Nutrition
BackgroundCardiovascular-kidney-metabolic (CKM) syndrome, a novel and multistage disorder recently proposed by the American Heart Association (AHA), highlights the intricate connection between cardiovascular, renal, and metabolic illnesses.
Dingyuan Tu, Dingyuan Tu, Xiaoli Zuo, Ping Li, Jianming Wang   +4 more
doaj   +1 more source

Association of cardiovascular-kidney-metabolic syndrome with depression and all-cause mortality: a population-based observational study

Frontiers in Nutrition
BackgroundCardiovascular-Kidney-Metabolic Syndrome (CKM) is a novel multi-system disease defined by the American Heart Association (AHA). This study aims to investigate the prevalence of depression in different stages of CKM syndrome and its relationship
Wei Liu, Zhijuan Li, Pu Ma
doaj   +1 more source

Real‐World Effectiveness and Safety of Finerenone in People With Type 2 Diabetes and Chronic Kidney Disease: A Spanish Multicentre Retrospective Observational Study (MEDFINE‐RWD)

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9461-9472, October 2026.
ABSTRACT Aim Although finerenone has shown efficacy in randomized trials, evidence from routine clinical practice remains limited. We aimed to assess the real‐world effectiveness and safety of finerenone in people with type 2 diabetes (PWT2D) and chronic kidney disease (CKD), with a particular focus on residual cardiorenal risk as reflected by changes ...
Oscar Moreno‐Pérez, Antonio Tejera‐Muñoz, Patricia Tomás‐Gómez, Federico Vázquez‐San Miguel, Virginia Soria‐Utrilla, Ada María Roldán‐Sánchez, Maya Sánchez‐Baya, Jersy Cárdenas‐Salas, Blanca Timón‐Vázquez, Juan J. Gorgojo‐Martínez, Ines Modrego‐Pardo, Irea Fernández‐Xove, Jose Carlos Fernández‐García, Rebeca Reyes‐García   +13 more
wiley   +1 more source

Association of dietary niacin intake with cardiovascular-kidney-metabolic syndrome risk and mortality

American Journal of Preventive Cardiology
Background: Dietary niacin, an essential nutrient, protects against metabolic diseases; however, its association with Cardiovascular-Kidney-Metabolic (CKM) syndrome and related mortality remains poorly understood.
Xuecui Zhang, Debin Chen, Liangwei Wu, Yizhou Zhuang, Jiakang Yang, Yaojie Wang, Yining Li, Qijun Zhang, Jianhui Zhao   +8 more
doaj   +1 more source

Inverse relationship between dietary index for gut microbiota and cardiovascular-kidney-metabolic syndrome among the general adult population

Scientific Reports
Cardiovascular-kidney-metabolic (CKM) syndrome is defined as the complex interaction of metabolic diseases such as metabolic syndrome (MS), chronic kidney disease (CKD), and cardiovascular disease (CVD).
Yixiao Zhao, Xiaolin Zhao, Jianping Cheng   +2 more
doaj   +1 more source