Results 41 to 50 of about 1,914 (161)

Genetic diversity of highly pathogenic avian influenza H5N6 and H5N8 viruses in poultry markets in Guangdong, China, 2020-2022

Journal of Virology
H5 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 (Gs/Gd) lineage continue to evolve and cause outbreaks in domestic poultry and wild birds, with sporadic spillover infections in mammals.
Kang Yang, Sarea Nizami, Shu Hu, Lirong Zou, Huishi Deng, Jiamin Xie, Qianfang Guo, Kimberly M. Edwards, Vijaykrishna Dhanasekaran, Hui-Ling Yen, Jie Wu   +10 more
doaj   +1 more source

Highly pathogenic avian influenza A virus (HPAIV) H5N1 infection in two European grey seals (Halichoerus grypus) with encephalitis

Emerging Microbes and Infections, 2023
Recent reports documenting sporadic infections in carnivorous mammals worldwide with highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b have raised concerns about the potential risk of adaptation to sustained transmission in mammals ...
Monica Mirolo, Anne Pohlmann, Ann Kathrin Ahrens, Bianca Kühl, Ana Rubio-Garcìa, Katharina Kramer, Ulrike Meinfelder, Tanja Rosenberger, Hannah Leah Morito, Martin Beer, Martin Ludlow, Peter Wohlsein, Wolfgang Baumgärtner, Timm Harder, Albert Osterhaus   +14 more
doaj   +1 more source

H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows

Nature
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b H5N1 infections were reported in dairy cows in Texas, USA1. Rapid dissemination to more than 380 farms in 14 states followed2. Here we provide results of two independent clade 2.3.4.4b experimental infection studies evaluating the oronasal susceptibility to and transmission ...
Nico Joel Halwe, Konner Cool, Angele Breithaupt, Jacob Schön, Jessie D. Trujillo, Mohammed Nooruzzaman, Taeyong Kwon, Ann Kathrin Ahrens, Tobias Britzke, Chester D. McDowell, Ronja Piesche, Gagandeep Singh, Vinicius Pinho dos Reis, Sujan Kafle, Anne Pohlmann, Natasha N. Gaudreault, Björn Corleis, Franco Matias Ferreyra, Mariano Carossino, Udeni B. R. Balasuriya, Lisa Hensley, Igor Morozov, Lina M. Covaleda, Diego G. Diel, Lorenz Ulrich, Donata Hoffmann, Martin Beer, Juergen A. Richt   +27 more
openaire   +2 more sources

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, Chile

Emerging Infectious Diseases, 2023
In December 2022, highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus emerged in Chile. We detected H5N1 virus in 93 samples and obtained 9 whole-genome sequences of strains from wild birds. Phylogenetic analysis suggests multiple viral introductions into South America.
Naomi Ariyama, Catalina Pardo-Roa, Gabriela Muñoz, Carolina Aguayo, Claudia Ávila, Christian Mathieu, Leonardo I. Almonacid, Rafael A. Medina, Barbara Brito, Magdalena Johow, Victor Neira   +10 more
openaire   +3 more sources

Cross-neutralization of Korea H5N1 clade 2.3.4.4b isolates using the WHO candidate vaccine virus-derived ferret antisera

Vaccine: X
Recent infections and transmissions of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses in humans and animals pose a significant global public health threat.
Jeong-Hyun Nam, Yong Jun Choi, Bo Min An, Jee Eun Rhee, Eun-Jin Kim   +4 more
doaj   +1 more source

Novel Clade 2.3.4.4b Highly Pathogenic Avian Influenza A H5N8 and H5N5 Viruses in Denmark, 2020

Viruses, 2021
Since late 2020, outbreaks of H5 highly pathogenic avian influenza (HPAI) viruses belonging to clade 2.3.4.4b have emerged in Europe. To investigate the evolutionary history of these viruses, we performed genetic characterization on the first HPAI ...
Yuan Liang, Jakob N. Nissen, Jesper S. Krog, Solvej Ø. Breum, Ramona Trebbien, Lars E. Larsen, Charlotte K. Hjulsager   +6 more
doaj   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Intraductal infection with H5N1 clade 2.3.4.4b influenza virus

Journal of Virology
Abstract The ongoing outbreak of highly pathogenic avian influenza (HPAI) H5N1 of the clade 2.3.4.4b in dairy cows has led to numerous questions including how the virus transmits amongst cattle given the limited respiratory infection. One hypothesis is that the virus is spreading through fomites from udder to udder. In these studies, we
Ericka Kirkpatrick Roubidoux, Victoria Meliopoulos, Brandi Livingston, Pamela H. Brigleb, Stacey Schultz-Cherry   +4 more
openaire   +3 more sources

Modulation of lethal HPAIV H5N8 clade 2.3.4.4B infection in AIV pre-exposed mallards [PDF]

Emerging Microbes & Infections, 2020
In 2016/2017, a severe epidemic of HPAIV H5N8 clade 2.3.4.4 group B (H5N8B) affected Europe. To analyse the role of mallards in the spatiotemporal dynamics of global HPAIV H5N8B dispersal, mallards (Anas platyrhynchos), naturally exposed to various AIV and therefore seropositive, were challenged with H5N8B.
Koethe, Susanne, Ulrich, Lorenz, Ulrich, Reiner, Amler, Susanne, Graaf, Annika, Harder, Timm C., Grund, Christian, Mettenleiter, Thomas C., Conraths, Franz J., Beer, Martin, Globig, Anja   +10 more
openaire   +4 more sources

Cellular tropism of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b viruses in human respiratory and bovine mammary epithelial cells

Microbiology Spectrum
The recent introduction and spread of HPAI A(H5N1) clade 2.3.4.4b viruses to U.S. dairy cattle demonstrate their ability to adapt to new mammalian hosts. Although multiple A(H5N1) genotypes have caused human infections, only two clade 2.3.4.4b genotypes (
Nicole Brock, Hui Zeng, Claudia Pappas, Troy J. Kieran, Xiangjie Sun, Joanna A. Pulit-Penaloza, Terrence M. Tumpey, Taronna R. Maines, Jessica A. Belser   +8 more
doaj   +1 more source