Modular, Tricomponent, and Concurrent One-Pot Synthesis of Libraries of γ-Keto Sulfones and γ-Keto Phosphine Oxides using Brønsted Acidic Eutectic Mixtures. [PDF]
This study presents a sustainable, metal‐free, one‐pot synthesis of γ‐keto sulfones and phosphine oxides using a ChCl/p‐TSA·H2O eutectic mixture. The method enables regioselective CC and CX bond formation under mild conditions, aligning with Green Chemistry Principles.
Ramos-Martín M +2 more
europepmc +2 more sources
Sulphur Analogues of Homoisoflavonoids as Potential Treatments for Neovascular Eye Diseases. [PDF]
Neovascular eye diseases are characterised by the abnormal growth of often fragile blood vessels in the eye. Treatment focuses on reducing angiogenesis as well as reducing oxidative stress induced inflammation, a key underlying cause. Synthetic sulphur analogues of naturally occurring homoisoflavonoids, synthesised in three steps, have shown promise as
Hiles JD +9 more
europepmc +2 more sources
Synthesis, Chemistry and Applications of 5-Hydroxymethyl-furfural And Its Derivatives [PDF]
The prospect of exciting research activity in the chemistry of furfural derived compounds such as 5-hydroxymethylfurfural (HMF), 2,5-furandicarbaldehyde and 2,5-furan-dicarboxylic acid prompted the writing of this article.
Lewkowski, Jarosław
core +1 more source
Synthesis and Antibacterial Activity of Chalcones and Pyrimidine-2-ones
Some new chalcones have been prepared by Claisen-schmidt condensation of ketone and different aromatic aldehydes. These chalcones on condensation with urea in presence of acid gave Pyrimidine-2-ones.
A. K. Parekh, K. K. Desai
doaj +1 more source
3-(2-Fluorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one
The title compound, C16H13FO2, was prepared from 4-methoxyhypnone and 2-fluorobenzophenone by a Claisen–Schmidt condensation reaction. The dihedral angle between the two benzene rings is 31.99 (2)°.
Huan-Mei Guo
doaj +1 more source
Genetics of Polyketide Metabolism in Aspergillus nidulans [PDF]
metabolite
Adams +62 more
core +11 more sources
STUDY OF THE SYNTHESIS METHODS OF 1,3-ARYL(HETERYL)PROPENONE
In this work, we refer to the study of recent specialized literature, where some syntheses methods of chalcone derivatives are described. These substances show a very pronounced anticancer activity, having a protective action in the cellular system ...
USM ADMIN
doaj
Diarylidene acetones (DAA) (1-5) had been prepared by the condensation of acetone with substituted benzaldehydes via Claisen-Schmidt reaction, DAA’s brought to condense with anthrone to afford the title compounds (6-10) through Michael addition.
Mohammed S. Hussein +2 more
doaj +1 more source
Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces [PDF]
Chalcones belong to the flavonoid family which constitutes one of the major classes of naturally occurring oxygen heterocyclic compounds. The alpha,beta-unsaturated carbonyl system of chalcones possesses two electrophilic reactive centers allowing them ...
Albuquerque, Hélio +3 more
core +1 more source
The Synthesis and Spectral Properties of Benzofuran Derivative bis-Chalcone
Khellin, a natural furanochromone, was isolated from the fruits of Ammi visnaga L. by using a rapid and easy technique. It was then hydrolyzed with 10% KOH to obtain khellinone. From the Claisen-Schmidt condensation of khellinone with terephthalaldehyde,
Neslihan Beyazit
doaj +1 more source

