Abstract Biofuels undergo oxidative degradation, which reduces their storage stability and efficiency, hindering their large‐scale adoption and integration into the global energy matrix. To address this issue, we synthesized and characterized four novel quinolinone–chalcone derivatives (substituted with Br, Cl, OCH3 and OCH2CH3) as potential ...
Vitor S. Duarte +8 more
wiley +1 more source
Thioxanthone: A Benchmark Photocatalyst for Organic Synthesis
Thioxanthone is a highly versatile and effective organocatalyst for photochemical applications, with its low‐toxicity, metal‐free structure driving growing interest in sustainable photocatalysis. Building on our previous 2021 review, this update covers advances from 2021–2025 in thioxanthone‐based synthetic organic photochemistry – excluding ...
Vera P. Demertzidou +2 more
wiley +1 more source
Synthesis of Some Novel Chalcone and 3,5‐Disubstituted Pyrazoline Derivatives: Evaluation of Their α‐Amylase and α‐Glucosidase Inhibitory Activities In Vitro and In Silico [PDF]
A novel pyrazoline derivative (P2) was synthesized and demonstrated potent α‐glucosidase inhibition (IC50 = 2.10 µM), significantly surpassing acarbose and highlighting its promise as an effective oral antidiabetic agent. ABSTRACT This study reports the synthesis of some novel chalcone (C1–C3) and 3,5‐disubstituted pyrazoline derivatives (P1–P3 ...
Erbay F +6 more
europepmc +2 more sources
Effect of Water‐Repellent Treatment of Heating Surface on a Leidenfrost Droplet
This study examined Leidenfrost droplet flow on heated surfaces with and without water‐repellent treatment. PIV showed that internal flow velocity rose with temperature and was higher on treated surfaces due to earlier vapor film formation. The results indicate that water‐repellent treatment lowers the Leidenfrost temperature and enhances droplet ...
Kenta Kotera +4 more
wiley +1 more source
Synthesis and Biological Evaluation of Some New Chalcones Containing 2,5-Dimethylfuran Moiety
A series of new chalcones (3a-g) were prepared by Claisen-Schmidt condensation of 3-acetyl-2,5-dimethylfuran with various substituted aromatic aldehydes in presence of aqueous solution of potassium hydroxide and ethanol at room temperature.
S. Sridhar +2 more
doaj +1 more source
Five novel chalcones were synthesised by condensing 2-hydroxy-1-acetonaphthone with aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen-Schmidt condensation and another five novel chalcones were ...
Y. Rajendra Prasad +3 more
doaj +1 more source
Original enzyme-catalyzed synthesis of chalcones: Utilization of hydrolase promiscuity [PDF]
E-chalcone was obtained with very high stereoselectivity for the first time by an enzyme-catalyzed Claisen-Schmidt condensation between benzaldehyde and acetophenone.
Mitrev Yavor N. +4 more
doaj +1 more source
A Highly Efficient Method for Synthesis of Bisarylmethylidenes of Cyclic Ketones in [BMIm]Cl/NaOH System as New and Recyclable Catalyst [PDF]
An ionic liquid 1-Butyl-3-methylimidazoliumchloride[BMIm]Cl/sodium hydroxide system, was employed as a catalyst for the fast and one-pot crossed aldol-condensation of various aromatic aldehydes and cyclic ketones, to produce a variety of substituted α,α'-
Javad Eslami +2 more
core +1 more source
Structure−Activity Relationships of New 1‐Aryl‐1H‐Indole Derivatives as SARS‐CoV‐2 Nsp13 Inhibitors
SARS‐CoV‐2 nsp13 is a promising target to develop effective antivirals. Pursuing the studies, new indolyl derivatives to deepen SARs are designed. The newly synthesized N‐aryl indoles are active vs both nsp13‐associated activities. They exert antiviral activity vs SARS‐CoV‐2 infected cells with no cytotoxicity.
Valentina Noemi Madia +18 more
wiley +1 more source
Skeletal Rearrangements of Amides via Breaking Inert Bonds
This review highlights advances in amide skeletal rearrangement reactions over the past two decades, categorized by the initial bond cleavages: C─N bond cleavage, C─C bond cleavage, and C═O bond activation. It summarizes emerging strategies, mechanistic insights, and synthetic applications, providing a focused perspective on recent developments in this
Rui Zhang, Guangbin Dong
wiley +1 more source

