A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Reply to "Letter to the editor: methodological considerations in the benchmarking of AI-based protein-aptamer complex prediction". [PDF]
Zhao J, Tram K, Yan H, Li Y.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Author Correction: Ultra-low core loss in Fe-enriched soft magnetic ribbons enabled by nanostructure and high-frequency domain engineering. [PDF]
Gautam R +8 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Assessing ChatGPT vs. evidence-based online responses for polycystic ovary syndrome self-management and education: an international cross-sectional blinded survey of healthcare professionals. [PDF]
Graca S +5 more
europepmc +1 more source
Methodological Considerations in Interpreting Mortality Trends in Aortic Dissection Among Hypertensive Adults. [PDF]
Bibi H, Arif S.
europepmc +1 more source
Extraction, Purification, and Characterization of Tannase Produced by <i>Aspergillus terreus</i> PQ344456 and Its Textile Dye Degradation and Juice Clarification Features. [PDF]
Alhazmi NM.
europepmc +1 more source
Expression of Concern: Barbalho et al. Effects of Adding Single Joint Exercises to a Resistance Training Programme in Trained Women. <i>Sports</i> 2018, <i>6</i>, 160. [PDF]
Sports Editorial Office.
europepmc +1 more source

