Results 81 to 90 of about 557,267 (345)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

High efficiency digital RF power source with dual frequency mode

open access: yesDianzi Jishu Yingyong, 2019
As one of the core components of the RF power system, the RF power source has a fixed frequency and low conversion efficiency, which has become a bottleneck restricting the development of the RF power system.
Li Yadong   +4 more
doaj   +1 more source

Single-Flux-Quantum Bipolar Digital-to-Analog Converter Comprising Polarity-Switchable Double-Flux-Quantum Amplifier [PDF]

open access: yes, 2017
We present a single-flux-quantum (SFQ)-based digital-to-analog converter (DAC) generating bipolar output voltages, in which the key component is a polarity-switchable double-flux-quantum amplifier (PS-DFQA). The DAC comprised a dc/SFQ converter, an 8-bit
Hiroshi Shimada   +2 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Noise characterization of an atomic magnetometer at sub-millihertz frequencies [PDF]

open access: yes, 2015
Noise measurements have been carried out in the LISA bandwidth (0.1 mHz to 100 mHz) to characterize an all-optical atomic magnetometer based on nonlinear magneto-optical rotation.
Budker, D.   +5 more
core   +3 more sources

Compensated Current Injection circuit, theory and applications [PDF]

open access: yes, 2002
This paper presents a detailed description, analysis and example of practical application of a wide frequency band voltage-to-current converter. The converter is characterized by a combination of positive and negative feedback loops.
Giorgio Fontana   +3 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Comparative study of two Multilevel converters for Envelope amplifier [PDF]

open access: yes, 2009
Modern transmitters usually have to amplify and transmit signals with simultaneous envelope and phase modulation. Due to this property of the transmitted signal, linear power amplifiers (class A, B or AB) are usually used as a solution for the power ...
Alou Cervera, Pedro   +5 more
core  

Photoswitch-based Class E microwave power amplifer [PDF]

open access: yes
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf ...
Karabegovic, Armin, 1969-
core   +1 more source

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