The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2000 grantor: University of TorontoThis thesis presents the design and implementation of a Class-E power amplifier implemented in 0.35 [mu]m CMOS. The rationale behind the selection of the final topology is discussed in detail.
Kubowicz, Richard
core +3 more sources
A Class-E Amplifier for a Loosely Coupled Inductive Power Transfer System with Multiple Receivers
Energies, 2019 We present a method for optimizing the electronic power system for a new type of photobioreactor or photoreactor in general. In the case of photobioreactors, photosynthetic active microorganisms or cells are grown. A novel concept for the illumination of
Alexander Sutor +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Modeling and Optimization of Class-E Amplifier at Subnominal Condition in a Wireless Power Transfer System for Biomedical Implants [PDF]
, 2017 For the class-E amplifier in a wireless power transfer (WPT) system, the design parameters are always determined by the nominal model. However, this model neglects the conduction loss and voltage stress of MOSFET and cannot guarantee the highest ...
Shao Q(邵琪) +2 more
core
Optimisation of short pulse multi-stage Yb fiber amplifier systems using commercial gain-modelling software [PDF]
, 2006 We demonstrate the accuracy of commercial telecommunications industry software for modelling Yb-fiber amplifiers. Simulations enabled optimisation of a broad bandwidth ultra-short pulse four-stage amplifier system. The predicted results were confirmed by
D. J. Richardson +5 more
core +1 more source
Preliminary study of 50 W Class-E GaN FET amplifier for 6.78 MHz capacitive wireless power transfer
Journal of Mechatronics, Electrical Power, and Vehicular Technology, 2020 A preliminary study of Class-E radio frequency power amplifier for wireless capacitive power transfer (CPT) system is presented in this paper. Due to a limitation in coupling capacitance value, a high frequency operation of switching power inverter is ...
Aam Muharam +6 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Development and characterization of a medium power class D amplifier [PDF]
, 2021 The present work presents the creation and analysis of a class D amplifier, to carry out the amplification, the integrated circuit IRS2092 from IOR - Infineon Technologies was used, capable of managing, modulating and amplifying the signals, requiring
Santos, Giovanne Cavalcante
core
High efficiency digital RF power source with dual frequency mode
Dianzi Jishu Yingyong, 2019 As one of the core components of the RF power system, the RF power source has a fixed frequency and low conversion efficiency, which has become a bottleneck restricting the development of the RF power system.
Li Yadong +4 more
doaj +1 more source