Activation of class 1 integron integrase is promoted in the intestinal environment. [PDF]
Class 1 integrons are widespread genetic elements playing a major role in the dissemination of antibiotic resistance. They allow bacteria to capture, express and exchange antibiotic resistance genes embedded within gene cassettes.
Murielle Baltazar +7 more
doaj +7 more sources
Complex Class 1 Integron in a Clinical Escherichia coli Strain From Vietnam Carrying Both mcr-1 and blaNDM–1 [PDF]
The co-production of MCR and carbapenemase in Enterobacteriaceae has been previously reported. Here, we describe a clinical strain of Escherichia coli from Vietnam carrying both mcr-1 and blaNDM–1.
Hong-Ngoc Le-Vo +9 more
doaj +4 more sources
Polymorphisms of Gene Cassette Promoters of the Class 1 Integron in Clinical Proteus Isolates [PDF]
ObjectiveTo describe the polymorphisms of gene cassette promoters of the class 1 integron in clinical Proteus isolates and their relationship with antibiotic resistance.MethodsPolymorphisms of the gene cassette promoter in 153 strains of Proteus were ...
Linlin Xiao +13 more
doaj +4 more sources
Transmissible ST3-IncHI2 Plasmids Are Predominant Carriers of Diverse Complex IS26-Class 1 Integron Arrangements in Multidrug-Resistant Salmonella [PDF]
Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria.
Hang Zhao +4 more
doaj +2 more sources
Antimicrobial Resistance in Class 1 Integron-Positive Shiga Toxin-Producing Escherichia coli Isolated from Cattle, Pigs, Food and Farm Environment [PDF]
The aim of this study was to investigate the presence of class 1 integrons in a collection of Shiga toxin-producing Escherichia coli (STEC) from different origins and to characterize pheno- and genotypically the antimicrobial resistance associated to ...
Rocío Colello +7 more
doaj +2 more sources
High prevalence of class 1 integron, biofilm formation, and antimicrobial resistance profiles of Escherichia coli isolated from cattle, water, and soil in Bangladesh [PDF]
Background Antimicrobial resistance (AMR) is a global threat. Escherichia coli is an important reservoir of resistance genes, and the coexistence of mcr with class 1 integron (intI1) is alarming, mcr confers resistance to colistin, a last-resort ...
Md. Niamul Shahadat +3 more
doaj +2 more sources
Background: Clinical management of bacterial infections has faced significant difficulties in recent years due to the advent and spread of multiple drug-resistant (MDR) bacteria.
Ahmed Abdulkareem Almuttairi +1 more
doaj +1 more source
Salmonella enterica serovar Indiana (S. Indiana) has aroused widespread concern as an important zoonotic pathogen. The molecular mechanism of multidrug resistance (MDR) in S. Indiana is not known and should be assessed.
Xuefeng Wang +6 more
doaj +1 more source
Prevalence of integron classes in Gram-negative clinical isolated bacteria in Iran: a systematic review and meta-analysis [PDF]
Objective(s): Integrons, as a potential element in the distribution and maintenance of drug resistance, have thoroughly been established. It is known that the high prevalence of integrons in multidrug-resistant (MDR) clinical isolates has become a ...
Ali Pormohammad +3 more
doaj +1 more source
Objective: Shewanella algae is a zoonotic marine bacterium that causes a variety of infections in immunocompromised patients or those who have been exposed to seawater. The development of trimethoprim/sulfamethoxazole (TMP/SMX) resistance in S. algae are
Liu Chia-Wei +11 more
doaj +1 more source

