Activation of class 1 integron integrase is promoted in the intestinal environment. [PDF]
PLoS Genetics, 2022 Class 1 integrons are widespread genetic elements playing a major role in the dissemination of antibiotic resistance. They allow bacteria to capture, express and exchange antibiotic resistance genes embedded within gene cassettes.
Murielle Baltazar +7 more
doaj +6 more sources
Complex Class 1 Integron in a Clinical Escherichia coli Strain From Vietnam Carrying Both mcr-1 and blaNDM–1 [PDF]
Frontiers in Microbiology, 2019 The co-production of MCR and carbapenemase in Enterobacteriaceae has been previously reported. Here, we describe a clinical strain of Escherichia coli from Vietnam carrying both mcr-1 and blaNDM–1.
Hong-Ngoc Le-Vo +9 more
doaj +4 more sources
The function of integron-associated genes cassettes in Vibrio species: the tip of the iceberg [PDF]
Frontiers in Microbiology, 2013 The integron is a genetic element that incorporates mobile genes termed gene cassettes into a reserved genetic site via site-specific recombination. It is best known for its role in antibiotic resistance with one type of integron, the class 1 integron, a
Rita A Rapa +3 more
doaj +3 more sources
Transmissible ST3-IncHI2 Plasmids Are Predominant Carriers of Diverse Complex IS26-Class 1 Integron Arrangements in Multidrug-Resistant Salmonella [PDF]
Frontiers in Microbiology, 2018 Diverse mobile genetic elements (MGEs) including plasmids, insertion sequences, and integrons play an important role in the occurrence and spread of multidrug resistance (MDR) in bacteria.
Hang Zhao +4 more
doaj +2 more sources
Prevalence and characterization of integrons in blood culture
Annals of Clinical Microbiology and Antimicrobials, 2004 Background Class 1 integrons contain genetic elements for site-specific recombination, capture and mobilization of resistance genes. Studies investigating the prevalence, distribution and types of integron located resistance genes are important for ...
Gjernes Elisabet +4 more
doaj +3 more sources
Polymorphisms of Gene Cassette Promoters of the Class 1 Integron in Clinical Proteus Isolates [PDF]
Frontiers in Microbiology, 2019 ObjectiveTo describe the polymorphisms of gene cassette promoters of the class 1 integron in clinical Proteus isolates and their relationship with antibiotic resistance.MethodsPolymorphisms of the gene cassette promoter in 153 strains of Proteus were ...
Linlin Xiao +13 more
doaj +2 more sources
Antimicrobial Resistance in Class 1 Integron-Positive Shiga Toxin-Producing Escherichia coli Isolated from Cattle, Pigs, Food and Farm Environment [PDF]
Microorganisms, 2018 The aim of this study was to investigate the presence of class 1 integrons in a collection of Shiga toxin-producing Escherichia coli (STEC) from different origins and to characterize pheno- and genotypically the antimicrobial resistance associated to ...
Rocío Colello +7 more
doaj +2 more sources
High prevalence of class 1 integron, biofilm formation, and antimicrobial resistance profiles of Escherichia coli isolated from cattle, water, and soil in Bangladesh [PDF]
BMC MicrobiologyBackground Antimicrobial resistance (AMR) is a global threat. Escherichia coli is an important reservoir of resistance genes, and the coexistence of mcr with class 1 integron (intI1) is alarming, mcr confers resistance to colistin, a last-resort ...
Md. Niamul Shahadat +3 more
doaj +2 more sources
Using the class 1 integron-integrase gene as a proxy for anthropogenic pollution. [PDF]
ISME J, 2015 This is the final version of the article. Available from the publisher via the DOI in this record.Around all human activity, there are zones of pollution with pesticides, heavy metals, pharmaceuticals, personal care products and the microorganisms ...
Gillings MR +5 more
europepmc +2 more sources
Linking Clinical and Environmental Multidrug Resistance Plasmids Captured from the Tama River Flowing Through the Tokyo Megalopolis [PDF]
AntibioticsBackground: Plasmid-mediated horizontal transfer of antimicrobial resistance genes (ARGs) is a major driver of resistance dissemination across clinical and environmental settings.
Rin Yamazaki +8 more
doaj +2 more sources