Prevalence of Class 1 Integron and Antibiotic Resistance among Pseudomonas Aeruginosa Isolated from Patients Admitted to the Burn Unit at Taleghani Hospital in Ahvaz [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2015 Background: Pseudomonas aeruginosa is one of the major etiologic agents of nosocomial infection among burn patients that has high resistance to antibiotics. Integrons can extend antibiotic resistance genes among bacteria.
Seyyed Sajjad Khorramrooz +5 more
doaj +1 more source
Engineering a CRISPR Interference System To Repress a Class 1 Integron in Escherichia coli [PDF]
Antimicrobial Agents and Chemotherapy, 2020 Haifeng Zhao, Pingfang Tian
exaly +2 more sources
Multidrug and co-resistance patterns of non-fermenting Gram-negative bacilli involved in ventilator-associated pneumonia carrying class 1 integron in the North of Iran. [PDF]
Germs, 2017 Bagheri-Nesami M +8 more
europepmc +2 more sources
Definition of the attI1 site of class 1 integrons [PDF]
Microbiology, 2000 Integron-encoded integrases recognize two distinct types of recombination site: attI sites, found in integrons, and members of the 59-base element (59-be) family, found in the integron-associated gene cassettes. The class 1 integron integrase, IntI1, catalyses recombination between attI1 and a 59-be, two 59-be, or two attI1 sites, but events involving ...
Sally R, Partridge +5 more
openaire +5 more sources
Resistance integrons: class 1, 2 and 3 integrons [PDF]
Annals of Clinical Microbiology and Antimicrobials, 2015 As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang +9 more
openaire +2 more sources
Medical Journal of Babylon, 2023 Background: Clinical management of bacterial infections has faced significant difficulties in recent years due to the advent and spread of multiple drug-resistant (MDR) bacteria.
Ahmed Abdulkareem Almuttairi +1 more
doaj +1 more source
The Evolution of Class 1 Integrons and the Rise of Antibiotic Resistance [PDF]
Journal of Bacteriology, 2008 ABSTRACTClass 1 integrons are central players in the worldwide problem of antibiotic resistance, because they can capture and express diverse resistance genes. In addition, they are often embedded in promiscuous plasmids and transposons, facilitating their lateral transfer into a wide range of pathogens.
Michael, Gillings +6 more
openaire +2 more sources
Diversity of Class 1 Integron Gene Cassette Rearrangements Selected under Antibiotic Pressure. [PDF]
J Bacteriol, 2015 Barraud O, Ploy MC.
europepmc +2 more sources
Screening Foodstuffs for Class 1 Integrons and Gene Cassettes [PDF]
Journal of Visualized Experiments, 2015 Antibiotic resistance is one of the greatest threats to health in the 21st century. Acquisition of resistance genes via lateral gene transfer is a major factor in the spread of diverse resistance mechanisms. Amongst the DNA elements facilitating lateral transfer, the class 1 integrons have largely been responsible for spreading antibiotic resistance ...
Liette S, Waldron, Michael R, Gillings
openaire +2 more sources
Frontiers in Microbiology, 2022 Salmonella enterica serovar Indiana (S. Indiana) has aroused widespread concern as an important zoonotic pathogen. The molecular mechanism of multidrug resistance (MDR) in S. Indiana is not known and should be assessed.
Xuefeng Wang +6 more
doaj +1 more source