Results 71 to 80 of about 2,012,091 (336)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multidimensional stochastic differential equations with distributional drift [PDF]

open access: yes, 2014
This paper investigates a time-dependent multidimensional stochastic differential equation with drift being a distribution in a suitable class of Sobolev spaces with negative derivation order.
Elena Issoglio   +8 more
core   +5 more sources

The Trajectory-Coherent Approximation and the System of Moments for the Hartree-Type Equation

open access: yes, 2000
The general construction of quasi-classically concentrated solutions to the Hartree-type equation, based on the complex WKB-Maslov method, is presented.
Belov, V. V.   +2 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Existence of Periodic Solutions for a Class of Fourth-Order Difference Equation

open access: yesJournal of Function Spaces, 2022
We apply the continuation theorem of Mawhin to ensure that a fourth-order nonlinear difference equation of the form Δ4uk−2−akuαk+bkuβk=0 with periodic boundary conditions possesses at least one nontrivial positive solution, where Δuk=uk+1−uk is the ...
Jia Wei, Xiaoling Han, Fumei Ye
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Neutral delay equations from and for population dynamics

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2008
For a certain class of neutral differential equations it is shown that these equations can serve as population models in the sense that they can be interpreted as special cases or caricatures of the standard Gurtin-MacCamy model for a population ...
K. P. Hadeler
doaj   +1 more source

H\^older continuity of solutions of second-order non-linear elliptic integro-differential equations

open access: yes, 2010
This paper is concerned with H\"older regularity of viscosity solutions of second-order, fully non-linear elliptic integro-differential equations. Our results rely on two key ingredients: first we assume that, at each point of the domain, either the ...
Barles, Guy   +2 more
core   +3 more sources

Class number bounds and Catalan’s equation [PDF]

open access: yesMathematics of Computation, 1998
We improve a criterion of Inkeri and show that if there is a solution to Catalan’s equation x p − y q = ± 1 , \begin{equation}x^p-y^q=\pm 1,\end{equation} with p p and q q prime numbers greater than 3 ...
openaire   +1 more source

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