Results 91 to 100 of about 14,390,534 (297)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
, 2016 Neukirch has developed explicit and axiomatic class field theory, which applies to both local and global fields. One of the key ingredients in his theory is a $\hat{\mathbb{Z}}$-extension of the base field, and in the case of $\mathbb{Q}_p$, he uses the ...
Yoon, Seok Ho Jack
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A spectral theorem for a non-Archimedean valued field whose residue field is formally real
Extracta MathematicaeIn this paper, we will prove a spectral theorem for self-adjoint compactoid operators. Also, we will study the condition on which the coefficient field must be imposed.
K. Ishizuka
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Field‐capital theory and its implications for marketing [PDF]
, 2010 Purpose: This paper seeks to explore the applicability and implications of Bourdieu's field-capital theory for marketing using original research with a typical European society.
Tapp, Alan +3 more
core +1 more source
A new strategy to microscopic modeling of topological entanglement in polymers based on field theory
Nuclear Physics B, 2019 In this work a new strategy is proposed in order to build analytic and microscopic models of fluctuating polymer rings subjected to topological constraints.
Franco Ferrari
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Against Field Interpretations of Quantum Field Theory [PDF]
, 2008 I examine some problems standing in the way of a successful ``field interpretation'' of quantum field theory. The most popular extant proposal depends on the Hilbert space of ``wavefunctionals.'' But since wavefunctional space is unitarily equivalent to ...
Baker, David
core
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Local class field theory [PDF]
St. Petersburg Mathematical Journal, 2004 The author gives condition for a Henselian field \(F\) which imply that local class field theory is valid for \(F\) in the sense that for every finite Galois extension \(F_0\) of \(F\) the reciprocity map \(\text{Gal}(F_0/F) \to F^{\times}/N_{F_0/F}(F_0^{\times})\) induces an isomorphism of the projection to \(\text{Gal}(F_0/F)^{ab}\).
openaire +1 more source