The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Students' perspective of a mathematics extension programme designed with special interest in history : a thesis presented in partial fulfilment of the requirements for the degree of Master of Educational Studies (Mathematics) at Massey University [PDF]
, 2006 The current Mathematics in the New Zealand Curriculum (Ministry of Education, 1992) includes the development of mathematical talent as a major aim of mathematics education.
Nettleship, Eve
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Who takes the cake Effects of ECB monetary policy across income classes [PDF]
, 2019 This work provides evidence on the effects of monetary policy on the income class structure via stimulating economic activity and employment in Eurozone countries over the period 2007Q32016Q1.
Barcena-Martin, Elena Maria +2 more
core
Inversion of a mapping associated with the Aomoto-Forrester system
, 2013 This article is devoted to the study of a general class of Hamiltonian systems which extends the Calogero systems with external quadratic potential associated to any root system.
Caseiro, Raquel +2 more
core +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
EconomiesInterest rate dynamics are influenced by various economic factors, and central bank meetings play a crucial role concerning this subject matter. This study introduces a novel approach to modeling interest rates, focusing on the impact of central banks ...
Allan Jonathan da Silva, Jack Baczynski
doaj +1 more source
IMPACT OF THE APLICATION OF STUDENT FACILITATOR AND EXPLAINING LEARNING METHOD, RELATED TO THE STUDENT LEARNING INTEREST FOR TIK STUDY PROGRAME IN SMA N 1 MERTOYUDAN MAGELANG 2011/2012 [PDF]
, 2012 The reason of low learning interest basically generated by inappropriate method of study related to the material of the curriculum. For that reason, there should be an alternative learning method , the same reason why Student Facilitator and Explaining ...
Abram, Rinekso Langgeng
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source