Results 171 to 180 of about 12,130,137 (366)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Decoding cell-class specific roles of non-coding variants in human retina. [PDF]
VandenBosch LS +2 more
europepmc +1 more source
Effect of Promotional Strategy on Consumer Interest in Online Shopping at Shopee (Case Study on Students of the Faculty of Economics and Business Unismuh Makassar Management Study Program Class of 2018). [PDF]
Aris Pasigai, A Fitri
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Commentary on "detoxification of deoxynivalenol by pathogen-inducible tau-class glutathione transferases from wheat". [PDF]
Shendre L.
europepmc +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Efficacy of Flipped Classroom and Game Teaching in Experimental Teaching of Histology and Embryology. [PDF]
Ma B +7 more
europepmc +1 more source

