Results 21 to 30 of about 247,620 (208)

Explicit and Implicit Processes in Human Aversive Conditioning [PDF]

open access: yes, 2006
The ability to adapt to a changing environment is central to an organism’s success. The process of associating two stimuli (as in associative conditioning) requires very little in the way of neural machinery.
Carter, Ronald McKell
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Computational Models of Classical Conditioning: A Qualitative Evaluation and Comparison [PDF]

open access: yes, 2014
Classical conditioning is a fundamental paradigm in the study of learning and thus in understanding cognitive processes and behaviour, for which we need comprehensive and accurate models.
Alonso, E., Mondragon, E., Sahota, P.
core  

Associative memory stored by functional novel pathway rather than modifications of preexisting neuronal pathways [PDF]

open access: yes, 2006
Associative conditioning involves changes in the processing pathways activated by sensory information to link the conditioned stimulus (CS) to the conditioned behavior.
Benjamin, Paul R   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Lower and Upper Conditioning in Quantum Bayesian Theory [PDF]

open access: yes, 2018
Updating a probability distribution in the light of new evidence is a very basic operation in Bayesian probability theory. It is also known as state revision or simply as conditioning.
Jacobs, Bart
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Selective inference after feature selection via multiscale bootstrap

open access: yes, 2021
It is common to show the confidence intervals or $p$-values of selected features, or predictor variables in regression, but they often involve selection bias. The selective inference approach solves this bias by conditioning on the selection event.
Shimodaira, Hidetoshi, Terada, Yoshikazu
core  

Visual Learning In The Perception Of Texture: Simple And Contingent Aftereffects Of Texture Density [PDF]

open access: yes, 1996
Novel results elucidating the magnitude, binocularity and retinotopicity of aftereffects of visual texture density adaptation are reported as is a new contingent aftereffect of texture density which suggests that the perception of visual texture density ...
Durgin, Frank H., Proffitt, D. R.
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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