Results 31 to 40 of about 1,326 (98)

A Variational Formulation of European Option Prices in the 1‐Hypergeometric Stochastic Volatility Model

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT The paper proposes a variational analysis of the 1‐hypergeometric stochastic volatility model for pricing European options. The methodology involves the derivation of estimates of the weak solution in a weighted Sobolev space. The weight is closely related to the stochastic volatility dynamic of the model.
José Da Fonseca, Wenjun Zhang
wiley   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

open access: yesExperimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu   +7 more
wiley   +1 more source

Exact analytical solutions of the Bloch equation for the hyperbolic‐secant and chirp pulses

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 5, Page 2140-2149, November 2025.
Abstract Purpose To improve the accuracy and generality of analytical solutions of the Bloch equation for the hyperbolic‐secant (HS1) and chirp pulses in order to facilitate application to truncated and composite pulses and use in quantitative methods.
Ryan H. B. Smith   +2 more
wiley   +1 more source

Irisin‐Loaded Cerium‐Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
The Irisin/Ce‐MBGNs delivery system can slowly release myokine Irisin for vital pulp therapy. Irisin/Ce‐MBGNs can enhance mitochondrial function and promote the differentiation of inflammatory macrophages toward M2‐Mφ, thereby regulating the immune response mechanism of inflamed dental pulp.
Mingxin Wang   +9 more
wiley   +1 more source

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan   +4 more
wiley   +1 more source

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li   +5 more
wiley   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

open access: yesiMeta, Volume 4, Issue 5, October 2025.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang   +12 more
wiley   +1 more source

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

open access: yesPlant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang   +8 more
wiley   +1 more source

Integrative single‐cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer

open access: yesClinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Twenty‐four meta‐programs and forty‐two non‐epithelial cells subtypes were identified in gastrointestinal tract cancer using over one million cells. Esophageal cancer (EC), gastric cancer (GC) and colorectal cancer (CRC) display unique epithelial characteristics influenced by specialized tumor microenvironment.
Chuwen Sun   +7 more
wiley   +1 more source

Molecular Subtypes and Risk Prediction Model Based on Malignant Cell Differentiation Trajectories in Breast Cancer

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Breast cancer (BRCA) is characterised by complex cellular heterogeneity and differentiation hierarchies, which play a crucial role in bone metastasis and therapeutic resistance. However, existing classification systems remain inadequate in capturing these complexities, limiting their effectiveness in guiding treatment strategies.
Penghui Yan   +11 more
wiley   +1 more source

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