Results 61 to 70 of about 581,509 (321)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Complex Moduli of Physical Quanta
, 2004 Classical mechanics can be formulated using a symplectic structure on classical phase space, while quantum mechanics requires a complex-differentiable structure on that same space.
JOSÉ M. ISIDRO, Montesinos M.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Classical Logic in the Quantum Context
Quantum Reports, 2020 It is generally accepted that quantum mechanics entails a revision of the classical propositional calculus as a consequence of its physical content. However, the universal claim according to which a new quantum logic is indispensable in order to model ...
Andrea Oldofredi
doaj +1 more source
Quantum-Mechanical Dualities on the Torus
, 2003 On classical phase spaces admitting just one complex-differentiable structure, there is no indeterminacy in the choice of the creation operators that create quanta out of a given vacuum.
Isidro J. M. +5 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Generalized Uncertainty Principle, Classical Mechanics, and General Relativity
Physics Letters B, 2020 The Generalized Uncertainty Principle (GUP) has been directly applied to the motion of (macroscopic) test bodies on a given space-time in order to compute corrections to the classical orbits predicted in Newtonian Mechanics or General Relativity.
Roberto Casadio, Fabio Scardigli
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Czy możemy wykazać istnienie zjawisk całkowicie przypadkowych?
Zagadnienia Filozoficzne w Nauce, 2018 I show how classical and quantum physics approach the problem of randomness and probability. Contrary to popular opinions, neither we can prove that classical mechanics is a deterministic theory, nor that quantum mechanics is a nondeterministic one.
Marek Kuś
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The Formulations of Classical Mechanics with Foucault’s Pendulum
Physics, 2020 Since the pioneering works of Newton (1643–1727), mechanics has been constantly reinventing itself: reformulated in particular by Lagrange (1736–1813) then Hamilton (1805–1865), it now offers powerful conceptual and mathematical tools for the exploration
Nicolas Boulanger, Fabien Buisseret
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