Results 81 to 90 of about 2,564,919 (305)

Theoretical Physics: A Primer for Philosophers of Science

open access: yesPrincipia: An International Journal of Epistemology, 2009
We give a overview of the main areas in theoretical physics, with emphasis on their relation to Lagrangian formalism in classical mechanics. This review covers classical mechanics; the road from classical mechanics to Schrödinger’s quantum mechanics ...
Francisco Antonio Doria
doaj  

Complex Moduli of Physical Quanta

open access: yes, 2004
Classical mechanics can be formulated using a symplectic structure on classical phase space, while quantum mechanics requires a complex-differentiable structure on that same space.
JOSÉ M. ISIDRO, Montesinos M.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Classical Limit of Quantum Mechanics for Damped Driven Oscillatory Systems: Quantum–Classical Correspondence

open access: yesFrontiers in Physics, 2021
The investigation of quantum–classical correspondence may lead to gaining a deeper understanding of the classical limit of quantum theory. I have developed a quantum formalism on the basis of a linear invariant theorem, which gives an exact quantum ...
Jeong Ryeol Choi
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Classicalization of Quantum Mechanics: Classical Radiation Damping Without the Runaway Solution

open access: yesPhysics
In this paper, we review a new treatment of classical radiation damping, which resolves a known contradiction in the Abraham–Lorentz equation that has long been a concern. This radiation damping problem has already been solved in quantum mechanics by the
Tomio Petrosky   +2 more
doaj   +1 more source

A symplectic integrator for molecular dynamics on a hypersphere

open access: yesCondensed Matter Physics, 2020
We present a reversible and symplectic algorithm called ROLL, for integrating the equations of motion in molecular dynamics simulations of simple fluids on a hypersphere Sd of arbitrary dimension d. It is derived in the framework of geometric algebra and
J.-M. Caillol
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Classical Logic in the Quantum Context

open access: yesQuantum Reports, 2020
It is generally accepted that quantum mechanics entails a revision of the classical propositional calculus as a consequence of its physical content. However, the universal claim according to which a new quantum logic is indispensable in order to model ...
Andrea Oldofredi
doaj   +1 more source

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