Results 301 to 310 of about 137,516 (336)
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Neutrophilic asthma features increased airway classical monocytes
Clinical & Experimental Allergy, 2021AbstractBackgroundMonocytes and macrophages are critical innate immune cells of the airways. Despite their differing functions, few clinical studies discriminate between them and little is known about their regulation in asthma.ObjectiveWe aimed to distinguish and quantify macrophages, monocytes and monocyte subsets in induced sputum and blood and ...
Natalie M. Niessen +6 more
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Transcriptomic Network Support Distinct Roles of Classical and Non-Classical Monocytes in Human
International Reviews of Immunology, 2014Classical and non-classical monocytes are two well-defined subsets of monocytes displaying distinct roles. They differentially express numerous genes relevant to their primary role. Using five independent transcriptomic microarray datasets, we ruled out several inconsistent genes and identified common genes consistently overexpressed either in ...
Anbazhagan +4 more
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The stimulation of an osteogenic response by classical monocyte activation
Biomaterials, 2011The monocyte/macrophage system plays a central role in host defense, wound healing and immune regulation at biomaterial surfaces. Monocytes can be classically and alternatively activated, and can be stimulated differently in response to variations in biomaterial surface properties.
Omar M, Omar +7 more
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Non-classical monocytes in systemic lupus erythematosus (SLE)
2023Ο Συστηματικός Ερυθηματώδης Λύκος (ΣΕΛ) είναι μια χρόνια, συστημική αυτοάνοση νόσος που εκδηλώνει ποικίλες κλινικές και μοριακές διαταραχές που αποδίδονται στην απώλεια αυτοανοχής στα νουκλεϊκά οξέα και άλλα ενδογενή αντιγόνα, με συνέπεια την παραγωγή αυτοαντισωμάτων. Η υπερβολική και μη αναστρέψιμη βλάβη των ιστών που προκαλείται από τα αυτοαντισώματα
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The American Journal of Pathology
Monocyte patrolling of the vasculature has been ascribed primarily to the non-classical monocyte subset. However, a recent study of the glomerular microvasculature provided evidence that both classical and non-classical monocytes undergo periods of intravascular retention and migration.
ZheHao Tan +5 more
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Monocyte patrolling of the vasculature has been ascribed primarily to the non-classical monocyte subset. However, a recent study of the glomerular microvasculature provided evidence that both classical and non-classical monocytes undergo periods of intravascular retention and migration.
ZheHao Tan +5 more
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Transplant Immunology, 2008
Monocytes mediate immune responses following solid organ transplantation via cytokine secretion and differentiation to macrophage/dendritic cell lineages. To date, the pleiotropic immunomodulatory effect of statins on human monocytes following human heart transplantation has yet to be elucidated.
Fildes, J. E. +6 more
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Monocytes mediate immune responses following solid organ transplantation via cytokine secretion and differentiation to macrophage/dendritic cell lineages. To date, the pleiotropic immunomodulatory effect of statins on human monocytes following human heart transplantation has yet to be elucidated.
Fildes, J. E. +6 more
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Classical Monocytes Shuttling for Precise Delivery of Nanotherapeutics to Glioblastoma
Advanced Healthcare MaterialsAbstractGlioblastoma (GBM) is the most aggressive brain tumor for which current therapies have limited efficacy. Immunosuppression and difficulties in accessing tumors with therapeutic agents are major obstacles for GBM treatments. Classical monocytes (CMs) possess the strongest infiltration among myeloid cells recruited into tumors during ...
Congwen Li +8 more
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Blood, 2015
Abstract Introduction: Myelofibrosis (MF) is a clonal myeloproliferative neoplasm that develops de novo (primary myelofibrosis) or transforms from polycythemia vera or essential thrombocytosis. MF is characterized by stem cell-derived clonal myeloproliferation, abnormal cytokine expression, bone marrow fibrosis, anemia, splenomegaly ...
Sanja Prijic +7 more
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Abstract Introduction: Myelofibrosis (MF) is a clonal myeloproliferative neoplasm that develops de novo (primary myelofibrosis) or transforms from polycythemia vera or essential thrombocytosis. MF is characterized by stem cell-derived clonal myeloproliferation, abnormal cytokine expression, bone marrow fibrosis, anemia, splenomegaly ...
Sanja Prijic +7 more
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DECREASE IN NON-CLASSICAL MONOCYTES IN MYASTHENIA GRAVIS PATIENTS
2022Circulating monocytes are mononuclear cells which are highly specialized in phagocytosis and antigen presentation, secrete a large range of different cytokines, and migrate to the tissues in response to infection and injury. Monocytes can be subdivided into three major subsets: the classical monocytes (CD14+CD16-), the intermediate monocytes (CD14+CD16+
Hemery, Edouard +6 more
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Targeting immunosuppressive classical monocytes prevents immunotherapy resistance
Leading Edge of Cancer Research Symposium: Poster Session, 2022B. Leticia Rodriguez +13 more
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