Results 1 to 10 of about 363,626 (259)

The Ontogeny of Monocyte Subsets [PDF]

Frontiers in Immunology, 2019
Classical and non-classical monocytes, and the macrophages and monocyte-derived dendritic cells they produce, play key roles in host defense against pathogens, immune regulation, tissue repair and many other processes throughout the body. Recent studies have revealed previously unappreciated heterogeneity among monocytes that may explain this ...
Alberto Yanez, Helen Goodridge, Goodridge Helen S   +2 more
exaly   +5 more sources

Monocytes in Uremia [PDF]

Toxins, 2020
Monocytes play an important role in both innate immunity and antigen presentation for specific cellular immune defense. In patients with chronic renal failure, as well as those treated with maintenance hemodialysis, these cells are largely dysregulated. There is a large body of literature on monocyte alterations in such patients.
Matthias Girndt, Bogusz Trojanowicz, Christof Ulrich   +2 more
openaire   +4 more sources

Susceptibility to Infections During Acute Liver Injury Depends on Transient Disruption of Liver Macrophage Niche

Frontiers in Immunology, 2022
Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact ...
Mateus Eustáquio Lopes, Brenda Naemi Nakagaki, Matheus Silvério Mattos, Gabriel Henrique Campolina-Silva, Gabriel Henrique Campolina-Silva, Raquel de Oliveira Meira, Pierre Henrique de Menezes Paixão, André Gustavo Oliveira, Lucas D. Faustino, Ricardo Gonçalves, Gustavo Batista Menezes   +10 more
doaj   +1 more source

Platelet Activity and Its Correlation with Inflammation and Cell Count Readings in Chronic Heart Failure Patients with Reduced Ejection Fraction

Medicina, 2021
Background and objectives: There has been an increasing interest in the role of inflammation in thrombosis complications in chronic heart failure (HF) patients.
Aušra Mongirdienė, Jolanta Laukaitienė, Vilius Skipskis, Lolita Kuršvietienė, Julius Liobikas   +4 more
doaj   +1 more source

AFM negatively regulates the infiltration of monocytes to mediate sepsis-associated acute kidney injury

Frontiers in Immunology, 2023
BackgroundSepsis is organ dysfunction due to the host’s deleterious response to infection, and the kidneys are one of the organs damaged in common sepsis.
Caiyun Guo, Youling Fan, Youling Fan, Jiurong Cheng, Yingdong Deng, Xiangsheng Zhang, Yanna Chen, Huan Jing, Wenjun Li, Pei Liu, Jiaqi Xie, Wenjun Ning, Hongtao Chen, Jun Zhou   +13 more
doaj   +1 more source

Mass cytometry and single-cell RNA sequencing reveal immune cell characteristics of active and inactive phases of Crohn’s disease

Frontiers in Medicine, 2023
ObjectivesFor Crohn’s disease (CD), the alternation of the active phase and inactive phase may be related to humoral immunity and cellular immunity. This study aims to understand the characteristics of immune cells in patients with active CD (CDa) and ...
Wenjia Lin, Shiying Liu, Zhuojian Huang, Haiwen Li, Tianyu Lu, Yongxin Luo, Jiamin Zhong, Zewen Xu, Yu Liu, Yanwu Li, Yanwu Li, Peiwu Li, Qian Xu, Jiazhong Cai, Jiazhong Cai, Huibiao Li, Xin-lin Chen   +16 more
doaj   +1 more source

Macrophage-Secreted CSF1 Transmits a Calorie Restriction-Induced Self-Renewal Signal to Mammary Epithelial Stem Cells

Cells, 2022
Calorie restriction enhances stem cell self-renewal in various tissues, including the mammary gland. We hypothesized that similar to their intestinal counterparts, mammary epithelial stem cells are insulated from sensing changes in energy supply ...
Anna Kosenko, Tomer Meir Salame, Gilgi Friedlander, Itamar Barash   +3 more
doaj   +1 more source

Distinct effector functions mediated by Fc regions of bovine IgG subclasses and their interaction with Fc gamma receptors

Frontiers in Immunology, 2023
Cattle possess three IgG subclasses. However, the key immune functions, including complement and NK cell activation, and enhancement of phagocytosis, are not fully described for bovine IgG1, 2 and 3.
Alistair Noble, Basudev Paudyal, John C. Schwartz, William Mwangi, Danish Munir, Elma Tchilian, John A. Hammond, Simon P. Graham   +7 more
doaj   +1 more source

Increased Monocyte Production of IL-6 after Toll-like Receptor Activation in Children with Autism Spectrum Disorder (ASD) Is Associated with Repetitive and Restricted Behaviors

Brain Sciences, 2022
The prevalence of autism spectrum disorder (ASD) has starkly increased, instigating research into risk factors for ASD. This research has identified immune risk factors for ASD, along with evidence of immune dysfunction and excess inflammation frequently
Heather K. Hughes, Charity E. Onore, Milo Careaga, Sally J. Rogers, Paul Ashwood   +4 more
doaj   +1 more source

Kinetic Changes of Peripheral Blood Monocyte Subsets and Expression of Co-Stimulatory Molecules during Acute Dengue Virus Infection

Pathogens, 2021
Monocytes, one of the main target cells for dengue virus (DENV) infection, contribute to the resolution of viremia and to pathogenesis. We performed a longitudinal study by a detailed phenotypic comparison of classical (CD14++CD16−, non-classical (CD14 ...
Sakaorat Lertjuthaporn, Rassamon Keawvichit, Korakot Polsrila, Kasama Sukapirom, Ampaiwan Chuansumrit, Kulkanya Chokephaibulkit, Aftab A. Ansari, Ladawan Khowawisetsut, Kovit Pattanapanyasat   +8 more
doaj   +1 more source