Results 31 to 40 of about 451,788 (298)

Causes and Consequences of Innate Immune Dysfunction in Cirrhosis

Frontiers in Immunology, 2019
Liver cirrhosis is an increasing health burden and public health concern. Regardless of etiology, patients with cirrhosis are at risk of a range of life-threatening complications, including the development of infections, which are associated with high ...
Katharine Margaret Irvine, Isanka Ratnasekera, Elizabeth E. Powell, Elizabeth E. Powell, David Arthur Hume   +4 more
doaj   +1 more source

Monocytes in the Rat

Immunobiology, 2000
We review our methods for definition and phenotypical characterisation of normal and activated rat monocytes. To obtain a comprehensive sample of all blood monocytes including cells from the marginal pool of the blood stream, we extensively perfuse the extrapulmonary circulation with cold PBS/EDTA.
V, Grau, A, Scriba, O, Stehling, B, Steiniger   +3 more
openaire   +2 more sources

Classical monocytes from patients with pancreatic ductal adenocarcinoma exhibit a significantly altered transcriptome profile compared with healthy volunteers [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorPancreatic Ductal Adenocarcinoma (PDAC) affects approximately 8000 people every ...
Cook, Jenny Anne
core   +4 more sources

The Relationship Between Monocyte/HDL Cholesterol Ratio and Clinical Outcomes in Acute Myocarditis Patients

, 2021
Objectives:Myocarditis is an inflammatory disease of the heart muscle. Inflammation and oxidative stress are known to play an important role in myocarditis pathogenesis. The aim of this study is to evaluate the relationship between clinical endpoints and
Sefa Ünal, Özge Çakmak Karaaslan, Murat Oğuz Özilhan, Orhan Maden, Firdevs Ayşenur Ekizler, Cem Çoteli   +5 more
core   +1 more source

The Leukocyte Subtype Counts and Ratios Can Effectively Predict the Risk of Arterial Stiffness Assessed by Cardio-Ankle Vascular Index: A Retrospective Study

Frontiers in Cardiovascular Medicine, 2021
Background: Arterial stiffness was the pathological basis and risk factor of cardiovascular diseases, with chronic inflammation as the core characteristic.
Yaoling Wang, Ruiyun Wang, Lijuan Bai, Yun Liu, Lihua Liu, Linfeng He, Benling Qi   +6 more
doaj   +1 more source

Dietary fats induce human monocyte activation in vitro

, 2007
In early atherosclerosis the frequency of activated monocytes in the peripheral circulation is amplified, and migration of monocytes into the walls of the aorta and large arteries is increased, due partly to de novo expression or activation of monocyte ...
De Pascale, C., Wheeler-Jones, C.P.D., Bentley, C., Avella, M., Botham, K.M., Bejta, F., Lawson, C.   +6 more
core   +1 more source

The monocyte system in haematological malignancies [PDF]

, 2020
Monocytes consist of classical, intermediate, and non-classical monocytes. In haematological malignancies, such as multiple myeloma and acute myeloid leukaemia, monocytes are affected by both the disease itself and the treatment patients receive.
Rundgren, Ida Marie
core   +1 more source

Single Cell RNA-Seq and Machine Learning Reveal Novel Subpopulations in Low-Grade Inflammatory Monocytes With Unique Regulatory Circuits

Frontiers in Immunology, 2021
Subclinical doses of LPS (SD-LPS) are known to cause low-grade inflammatory activation of monocytes, which could lead to inflammatory diseases including atherosclerosis and metabolic syndrome.
Jiyoung Lee, Jiyoung Lee, Shuo Geng, Song Li, Song Li, Liwu Li   +5 more
doaj   +1 more source

Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]

, 2012
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David, Richard E. Randall, Richard E. Randall (190211), Nash, A.A., Anthony A Nash, Hoeve, M.A., Marieke A Hoeve, Anthony A. Nash, Hoeve Marieke A., Nash, Anthony A., Dransfield, I., Marieke A. Hoeve (190207), David Jackson (84936), Richard E Randall, Randall Richard E., Jackson, David, Randall, R.E., Nash Anthony A., David Jackson, Jackson, D., Ian Dransfield (190213), Dransfield, Ian, Marieke A. Hoeve, Anthony A. Nash (190209), Randall, Richard E., Ian Dransfield, Hoeve, Marieke A., Dransfield Ian   +27 more
core   +1 more source

Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

Frontiers in Pharmacology
IntroductionFollowing spinal cord injury (SCI), blood-borne monocytes infiltrate the spinal cord, differentiate into macrophages, and dominate the lesion site.
Yonghui Hou, Yonghui Hou, Yage Zhang, Yage Zhang, Lin Ma, Lin Ma, Dan Luo, Dan Luo, Wanshun Wang, Wanshun Wang, Shunmei E., Chengxi Huang, Yu Hou, Yu Hou, Shudong Chen, Shudong Chen, Jiheng Zhan, Jiheng Zhan, Liangliang Xu, Liangliang Xu, Dingkun Lin, Dingkun Lin   +21 more
doaj   +1 more source