Results 21 to 30 of about 451,788 (298)

The Monocyte That Wasn’t* [PDF]

open access: yesCritical Care Medicine, 2015
This issue of Critical Care Medicine has a feature article entitled “Monocyte tumor necrosis factor-alpha converting enzyme catalytic activity and substrate shedding in sepsis and non-infectious systemic inflammation” (1). The authors eloquently demonstrate in a human translational study that monocyte tumor necrosis factor-alpha (TNF) converting enzyme
Philip A, Efron, Alicia M, Mohr
openaire   +2 more sources

Causal relationship between circulating immune cells and the risk of type 2 diabetes: a Mendelian randomization study

open access: yesFrontiers in Endocrinology, 2023
ObjectivesThough type 2 diabetes (T2D) has been known as a metabolic disease caused by multiple factors, the etiology remains insufficiently understood.
Jin Li   +5 more
doaj   +1 more source

Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma

open access: yesFrontiers in Oncology, 2023
Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the peripheral
Krystle L. Ong   +12 more
doaj   +1 more source

Effect of high glucose concentration on the synthesis of monocyte chemoattractant protein-1 in human peritoneal mesothelial cells: Involvement of protein kinase C [PDF]

open access: yes, 2001
Human peritoneal mesothelial cells (HMC) contribute to the activation and control of inflammatory processes in the peritoneum by their potential to produce various inflammatory mediators.
Lederer, Stephan R.   +9 more
core   +1 more source

Antigen presentation by monocytes and monocyte-derived cells [PDF]

open access: yesCurrent Opinion in Immunology, 2008
Monocytes are circulating mononuclear phagocytes with a fundamental capacity to differentiate into macrophages. This differentiation can, in the presence of the right environmental cues, be re-directed instead to dendritic cells (DCs). Recent advances have been made in understanding the role of monocytes and their derivatives in presenting antigen to ...
Gwendalyn J, Randolph   +2 more
openaire   +2 more sources

Learning in a simple biological system: a pilot study of classical conditioning of human macrophages in vitro

open access: yesBehavioral and Brain Functions, 2011
Recent advances in cell biology and gene regulation suggest mechanisms whereby associative learning could be performed by single cells. Therefore, we explored a model of classical conditioning in human macrophages in vitro.
Nilsonne Gustav   +4 more
doaj   +1 more source

The Time Course of Monocytes Infiltration After Acoustic Overstimulation

open access: yesFrontiers in Cellular Neuroscience, 2022
Cochlea macrophages regulate cochlea inflammation and may harbors the potentials to protect hearing function from injury, including acoustic overstimulation. Cochlea macrophage numbers increase at 3–7 days after acoustic stimulation.
Seung Ho Shin   +7 more
doaj   +1 more source

Assessing the Functional Heterogeneity of Monocytes in Human Septic Shock: a Proof-of-Concept Microfluidic Assay of TNFα Secretion

open access: yesFrontiers in Immunology, 2021
ObjectiveThe development of advanced single-cell technologies to decipher inter-cellular heterogeneity has enabled the dynamic assessment of individual cells behavior over time, overcoming the limitation of traditional assays.
Jean-François Llitjos   +17 more
doaj   +1 more source

Effects of different obesogenic diets on joint integrity, inflammation and intermediate monocyte levels in a rat groove model of osteoarthritis

open access: yesFrontiers in Physiology, 2023
Introduction: Obesogenic diets aggravate osteoarthritis (OA) by inducing low-grade systemic inflammation, and diet composition may affect OA severity. Here, we investigated the effect of diet on joint damage and inflammation in an OA rat model.Methods ...
K. Warmink   +7 more
doaj   +1 more source

Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis

open access: yesFrontiers in Pharmacology, 2019
Monocytes and macrophages are key drivers in the pathogenesis of inflammatory diseases. Epigenetic targets have been shown to control the transcriptional profile and phenotype of these cells.
Rosario Luque-Martin   +15 more
doaj   +1 more source

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