Results 11 to 20 of about 363,626 (259)

Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

Frontiers in Immunology, 2023
IntroductionMonocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated.
Tobias Schmidt, Tobias Schmidt, Alma Dahlberg, Alma Dahlberg, Elisabet Berthold, Petra Król, Petra Król, Sabine Arve-Butler, Sabine Arve-Butler, Emilia Rydén, Emilia Rydén, Seyed Morteza Najibi, Anki Mossberg, Anki Mossberg, Anders A. Bengtsson, Fredrik Kahn, Bengt Månsson, Robin Kahn, Robin Kahn   +18 more
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CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Viral myocarditis is characterized by leukocyte infiltration of the heart and cardiomyocyte death. We recently identified C‐C chemokine ligand (CCL) 17 as a proinflammatory effector of C‐C chemokine receptor 2–positive macrophages and ...
Guoshuai Feng, Cuige Zhu, Chieh‐Yu Lin, Andrea Bredemeyer, Irmgard Förster, Daniel Kreisel, Kory J. Lavine   +6 more
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Monocyte-endothelial cell interactions in vascular and tissue remodeling

Frontiers in Immunology, 2023
Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or pathophysiological conditions to orchestrate inflammation, angiogenesis, or tissue remodeling.
Mireia Medrano-Bosch, Blanca Simón-Codina, Wladimiro Jiménez, Wladimiro Jiménez, Elazer R. Edelman, Pedro Melgar-Lesmes, Pedro Melgar-Lesmes, Pedro Melgar-Lesmes   +7 more
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Intermediate Monocytes with PD-L1 and CD62L Expression as a Possible Player in Active SARS-CoV-2 Infection

Viruses, 2022
Monocytes play a role in viral biology, but little is known about the monocyte subpopulation in the course of COVID-19 disease. The aim of the study was the analysis of classical, intermediate and non-classical monocytes with expression of PD-L1 and ...
Elżbieta Rutkowska, Iwona Kwiecień, Krzysztof Kłos, Piotr Rzepecki, Andrzej Chciałowski   +4 more
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The Monocyte That Wasn’t* [PDF]

Critical Care Medicine, 2015
This issue of Critical Care Medicine has a feature article entitled “Monocyte tumor necrosis factor-alpha converting enzyme catalytic activity and substrate shedding in sepsis and non-infectious systemic inflammation” (1). The authors eloquently demonstrate in a human translational study that monocyte tumor necrosis factor-alpha (TNF) converting enzyme
Philip A, Efron, Alicia M, Mohr
openaire   +2 more sources

Rab Geranylgeranyltransferase Subunit Beta as a Potential Indicator to Assess the Progression of Amyotrophic Lateral Sclerosis

Brain Sciences, 2023
Background: Currently, there is no effective treatment for amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disorder. Many biomarkers have been proposed, but because ALS is a clinically heterogeneous disease with an unclear etiology ...
Jing Yang, Cheng Xin, Jia Huo, Xin Li, Hui Dong, Qi Liu, Rui Li, Yaling Liu   +7 more
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Causal relationship between circulating immune cells and the risk of type 2 diabetes: a Mendelian randomization study

Frontiers in Endocrinology, 2023
ObjectivesThough type 2 diabetes (T2D) has been known as a metabolic disease caused by multiple factors, the etiology remains insufficiently understood.
Jin Li, Qingmin Niu, Aiwei Wu, Yuchu Zhang, Liquan Hong, Hu Wang   +5 more
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Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma

Frontiers in Oncology, 2023
Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the peripheral
Krystle L. Ong, Marcus D. Davis, Kalyn K. Purnell, Hannah Cutshall, Harish C. Pal, Ashley N. Connelly, Christian X. Fay, Valeriya Kuznetsova, Elizabeth E. Brown, Elizabeth E. Brown, Zdenek Hel, Zdenek Hel, Zdenek Hel   +12 more
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Antigen presentation by monocytes and monocyte-derived cells [PDF]

Current Opinion in Immunology, 2008
Monocytes are circulating mononuclear phagocytes with a fundamental capacity to differentiate into macrophages. This differentiation can, in the presence of the right environmental cues, be re-directed instead to dendritic cells (DCs). Recent advances have been made in understanding the role of monocytes and their derivatives in presenting antigen to ...
Gwendalyn J, Randolph, Claudia, Jakubzick, Chunfeng, Qu   +2 more
openaire   +2 more sources

Learning in a simple biological system: a pilot study of classical conditioning of human macrophages in vitro

Behavioral and Brain Functions, 2011
Recent advances in cell biology and gene regulation suggest mechanisms whereby associative learning could be performed by single cells. Therefore, we explored a model of classical conditioning in human macrophages in vitro.
Nilsonne Gustav, Appelgren Alva, Axelsson John, Fredrikson Mats, Lekander Mats   +4 more
doaj   +1 more source