Results 71 to 80 of about 409,562 (267)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Generalizing "Charge without Charge" to Obtain Classical Analogs of Short-Range Interactions [PDF]
, 2007 Several decades ago, Wheeler and Misner presented a model of electric charge ("charge without charge") based on the topological trapping of electric field lines in wormholes.
Sharlow, Mark
core
A hybrid classical-quantum algorithm for solution of nonlinear ordinary differential equations
, 2022 A hybrid classical-quantum approach for the solution of nonlinear ordinary differential equations using Walsh-Hadamard basis functions is proposed. Central to this hybrid approach is the computation of the Walsh-Hadamard transform of arbitrary vectors ...
Vedula, Prakash, Shukla, Alok
core
, 2011 Intuitively speaking, a classical field theory is back-ground-independent if the structure required to make sense of its equations is itself subject to dynamical evolution, rather than being imposed ab initio.
Belot, Gordon, Gordon Belot
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2014 The classical solution to boundary value problems for noiistrongly hyperbolic equation of the second order. It is known that classical solution is the basis of the theory of numerical methods for boundary value problems for partial differential equations.
Korzyuk, V. I., Cheb, E. S.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
General solution of classical master equation for reducible gauge theories
, 2012 We give the general solution to the classical master equation (S,S)=0 for reducible gauge theories. To this aim, we construct a new coordinate system in the extended configuration space and transform the equation by changing variables.
A.V. Bratchikov
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source