Results 101 to 110 of about 1,109,799 (314)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Simon Grant, Monti, Martin Osherson, Daniel [PDF]

open access: yes
The classical theory of preference among monetary bets represents people as expected utility maximizers with nondecreasing concave utility functions. Critics of this account often rely on assumptions about preferences over wide ranges of total wealth. We
A Note on Concave Utility Functions
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

A Comparison of Classical Test Theory and Nonparametric Item Response Theory with Respect to the Effects of Testees’ Characteristics on Item Characteristics and vice versa [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2006
This study aimed at comparing Classical Test Theory and Nonparametric Item Response Theory with respect to the effect of testees’ characteristics on item characteristics and vice versa. The research method was of the applied, descriptive type.
Ali delavar   +2 more
doaj  

Evaluasi Karakteristik Psikometrik Tes Bakat Differensial dengan Teori Klasik

open access: yesHumanitas: Indonesian Psychological Journal, 2018
The aims of the research were to analyze the psychometric characteristics of a set Differential Aptitude Test (DAT) consisting of five subtests, they are: numerical, abstract reasoning, space relation, and mechanics.
Farida Agus Setiawati   +2 more
doaj   +1 more source

Experimental Test of Tracking the King Problem

open access: yes, 2019
In quantum theory, the retrodiction problem is not as clear as its classical counterpart because of the uncertainty principle of quantum mechanics. In classical physics, the measurement outcomes of the present state can be used directly for predicting ...
Cao, Zhu   +9 more
core   +1 more source

Measurement properties of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ): a study based on Classical Test Theory [PDF]

open access: hybrid, 2016
Lisette M. van Leeuwen   +6 more
openalex   +1 more source

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