Results 91 to 100 of about 13,154,921 (285)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

THE DEVELOPMENT OF HOTS-BASED TECHNICAL MECHANICAL SUBJECT INSTRUMENTS USING A CLASSICAL TEST THEORY APPROACH

Jurnal Pensil
The need for the development of instruments for higher-order thinking skills of vocational students related to the demands of the era and the lack of teachers’s capability on arrange it requires a strengthening in the learning evaluation process ...
Salma Maharani, Zidni Husnurofik, Eva Maria Sianturi, Awaluddin Tjalla, Lussy Dwiutami Wahyuni, Ninda Ayu Narassati   +5 more
doaj   +1 more source

PENGEMBANGAN DAN ANALISIS SOAL ULANGAN KENAIKAN KELAS SMA KELAS X BERDASARKAN CLASSICAL TEST THEORY DAN ITEM RESPONSE THEORY [PDF]

, 2011
Penelitian ini berjudul “Pengembangan dan Analisis Soal Ulangan Kenaikan Kelas SMA Kelas X Berdasarkan Classical Test Theory dan Item Response Theory”.
Ana Rofiati, -
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Gaining a Better Understanding of General Mattering Scale: An Application of Classical Test Theory and Item Response Theory

International Journal of Assessment Tools in Education, 2018
The current study shows applications of both classical test theory (CTT) and item response theory (IRT) to psychology data. The study discusses item level analyses of General Mattering Scale produced by two theories as well as strengths and weaknesses of
Mehmet Akif Karaman, Halil İbrahim Sarı   +1 more
doaj   +1 more source

An empirical comparison of item response theory and classical test theory item/person statistics [PDF]

, 2004
In the theory of measurement, there are two competing measurement frameworks, classical test theory and item response theory. The present study empirically examined, using large scale norm-referenced data, how the item and person statistics behaved under
Courville, Troy Gerard
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

KARAKTERISTIK BUTIR SOAL: CLASSICAL TEST THEORY VS ITEM RESPONSE THEORY? [PDF]

, 2019
This research aimes to describe the characteristic of UAS items theme 1 at the fourth grade of Primary School in Paramasan bawah village according to the item difficulties and discrimination. The sample of this research was 37 students who took the final
Ruslan, Rosnia, Sarea, Muh Syahrul
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Investigating Different Theory-Based Differential Item Functioning Methods Under Different Scoring Situations

International Journal of Assessment Tools in Education, 2017
This study intended to investigate theoperations of various theory-based Differential Item Functioning (DIF) methodsunder different scoring situations.
Hüseyin Selvi, Devrim Alıcı
doaj   +1 more source