Results 91 to 100 of about 12,640,498 (274)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Just a Test

open access: yes, 2018
An abstract abstract!An abstract ...
Test, Test
core  

Can Factor Scores be Used Instead of Total Score and Ability Estimation?

open access: yesInternational Journal of Assessment Tools in Education, 2019
Thepurpose of this study is to investigate whether factor scores can be usedinstead of ability estimation and total score. For this purpose, the relationshipsamong total score, ability estimation, and factor scores were investigated.
Abdullah Faruk Kılıç
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Examination of the psychometric properties of physical activity enjoyment scale (PACES) based on classical test theory and item response theory

open access: yesActa Psychologica
Enjoyment of physical activity is a key factor influencing exercise and sports participation. This study aimed to examine the psychometric properties of the Turkish adaptation of the Physical Activity Enjoyment Scale (PACES-8) using Classical Test Theory
Yasin Altın   +2 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

A Comparison of Classical Test Theory and Nonparametric Item Response Theory with Respect to the Effects of Testees’ Characteristics on Item Characteristics and vice versa [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2006
This study aimed at comparing Classical Test Theory and Nonparametric Item Response Theory with respect to the effect of testees’ characteristics on item characteristics and vice versa. The research method was of the applied, descriptive type.
Ali delavar   +2 more
doaj  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

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