Results 111 to 120 of about 13,154,921 (285)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Pigou's Theory of Unemployment: what classical macroeconomics really was

open access: yes, 2013
the paper is centred on Pigou’s core framework of Theory of Unemployment (TU) and his arguments on the determinants of unemployment in the short period are discussed. I will show what actually are the implicit assumptions in TU on the behavior of the non
DI MATTEO, MASSIMO
core   +1 more source

Examination of the psychometric properties of physical activity enjoyment scale (PACES) based on classical test theory and item response theory

open access: yesActa Psychologica
Enjoyment of physical activity is a key factor influencing exercise and sports participation. This study aimed to examine the psychometric properties of the Turkish adaptation of the Physical Activity Enjoyment Scale (PACES-8) using Classical Test Theory
Yasin Altın   +2 more
doaj   +1 more source

A Comparison of Classical Test Theory and Nonparametric Item Response Theory with Respect to the Effects of Testees’ Characteristics on Item Characteristics and vice versa [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2006
This study aimed at comparing Classical Test Theory and Nonparametric Item Response Theory with respect to the effect of testees’ characteristics on item characteristics and vice versa. The research method was of the applied, descriptive type.
Ali delavar   +2 more
doaj  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Test Submission

open access: yes, 2023
This is a sample submission generated by Vireo to test the repository deposit ...
Submitter, Test
core   +1 more source

Item analysis procedures based on classical and modern test theory in personality tests

open access: yes, 1998
Item analysis procedures based on Item-Response Theory, which can be seen as an extension of Classical Test Theory with additional advantages, were applied to a personality scale.
Somer, O
core  

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