Results 101 to 110 of about 13,154,921 (285)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Psychometric Properties of Difficulties in Emotion Regulation Scale-8 based on Classical test theory and Item-response theory [PDF]

Taḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: Difficulties in emotion regulation are associated with significant mental health challenges. It appears that having a brief and valid tool to identify these difficulties could be beneficial for clinicians and researchers.
Farhad Tanhaye Reshvanloo, Hiva Baharloo
doaj  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Comparison of Item Statistics of Physics Achievement Test using Classical Test and Item Response Theory Frameworks [PDF]

, 2013
In this study, the author examined the comparability of item statistics generated from the frameworks of classical test theory (CTT) and 2-parameter model of item response theory (IRT). A 60-item Physics Achievement Test was developed and administered to
Adegoke, Benson Adesina
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

A Comparative Study on Classical Test Theory and Rasch Model in Comprehensive Mental Ability Test (CMAT): A Pilot Test [PDF]

, 2017
This study is a comparative analysis of Classical Test Theory (CTT) and the Rasch Model in the pilot testing of Comprehensive Mental Ability Test (CMAT).
P. Manapsal, Josephine
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Comparison of the Classical Test Theory and the Rasch Model in the Analysis of Mastery Test of Concept Systems of Linear (SPLDV)

Prima: Jurnal Pendidikan Matematika
This study aims to compare the analysis of the quality of a measurement instrument for concept understanding using the classical test theory approach and the Rasch model. The analysis methods for instrument quality, including validity, reliability, item
Putu Aulia Ciptari, Ni Kadek Rini Purwanti, Ni Ketut Erawati   +2 more
doaj   +1 more source

Can Factor Scores be Used Instead of Total Score and Ability Estimation?

International Journal of Assessment Tools in Education, 2019
Thepurpose of this study is to investigate whether factor scores can be usedinstead of ability estimation and total score. For this purpose, the relationshipsamong total score, ability estimation, and factor scores were investigated.
Abdullah Faruk Kılıç
doaj   +1 more source

1st Lecture (17.10.2016): Repeating the Essentials of Classical Test Theory

, 2016
Topic: Introduction and Outline of the lecture, Repetition of the basic ideas of Classical Test Theory (CTT), Models of CTT, The model of essentially tau-equivalent ...
Multimediazentrum, Steyer, Rolf
core