Results 71 to 80 of about 118,285 (285)

Gaining a Better Understanding of General Mattering Scale: An Application of Classical Test Theory and Item Response Theory

International Journal of Assessment Tools in Education, 2018
The current study shows applications of both classical test theory (CTT) and item response theory (IRT) to psychology data. The study discusses item level analyses of General Mattering Scale produced by two theories as well as strengths and weaknesses of
Mehmet Akif Karaman, Halil İbrahim Sarı   +1 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

ANALYSIS OF CTT AND IRT ON NON-TEST MEASUREMENT INSTRUMENTS: MATHEMATICAL MINDSET SCALE

Jurnal Eduscience
Purpose – This study aims to determine empirically the appropriate number of items that meet all item selection criteria, from classical test theory to item response theory.
Priarti Megawanti, Nurimani Nurimani, Meyta Dwi Kurniasih   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

THE DEVELOPMENT OF HOTS-BASED TECHNICAL MECHANICAL SUBJECT INSTRUMENTS USING A CLASSICAL TEST THEORY APPROACH

Jurnal Pensil
The need for the development of instruments for higher-order thinking skills of vocational students related to the demands of the era and the lack of teachers’s capability on arrange it requires a strengthening in the learning evaluation process ...
Salma Maharani, Zidni Husnurofik, Eva Maria Sianturi, Awaluddin Tjalla, Lussy Dwiutami Wahyuni, Ninda Ayu Narassati   +5 more
doaj   +1 more source

Thermal-Safe Test Scheduling for Core-Based System-on-a-Chip Integrated Circuits

, 2005
Overheating has been acknowledged as a major problem during the testing of complex system-on-chip (SOC) integrated circuits. Several power-constrained test scheduling solutions have been recently proposed to tackle this problem during system integration.
Rosinger, Paul, Chakrabarty, Krishnendu, Al-Hashimi, Bashir   +2 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The development and preliminary validation of a brief scale of emotional distress in young people using combined classical test theory and item response theory approaches: The Brief Emotional Distress Scale for Youth (BEDSY)

, 2022
Reliable, valid, and brief measures are important for identifying young people in community contexts who experience mental health problems. This paper reports the development and preliminary validation of the Brief Emotional Distress Scale for Youth ...
Spence, Susan H, Rapee, Ronald M
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The application of measurement theory to tests in mathematics: a study of the goodness-of-fit of rasch model to the alis mathematics test [PDF]

, 2003
The scores provided by the International Test of Developed Ability (ITDA) have been used as an alternative baseline for comparing the progress of students in the A-level Information System (ALIS) project of U.K.
Kwan, Siu Kam
core