Results 81 to 90 of about 8,969 (298)
Towards a qualified classicism
, 1988 The intent of this thesis is to first, demonstrate that classicism remains valid as an underlying idea for the creation of architecture and second, that in order to exist in a meaningful and critical position, classicism must be 'qualified.' The term ...
Zajkowski, Michael M.
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Karel Vinařický: Between Classicism and Romanticism
, 2017 The study deals with Classicism in the work of Alois Josef Vinařický in the period 1820–1850, specifically. The analysis documents that in this time the markers of Classicism can be found in different constellations performing a variety of functions.
Tureček, Dalibor
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Classical Conditioning: Classical Yet Modern
Psychologica Belgica, 2018 This manuscript is part of a special issue to commemorate professor Paul Eelen, who passed away on August 21, 2016. Paul was a clinically oriented scientist, for whom learning principles (Pavlovian or operant) were more than salivary responses and lever presses.
openaire +5 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The beginnings of scholarship on early medieval book illumination (1700-1850): between classicism and ethnicity [PDF]
Journal of Art Historiography, 2020 This essay addresses historiographical and methodological issues about the very beginnings of the scholarship on early medieval manuscript illumination during the eighteenth and nineteenth centuries.
Charlotte Denoël
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
MIKHAIL EMELYANOVICH EMELYANOV, THE FIRST ARCHITECT OF THE HOLY TRINITY CATHEDRAL OF EKATERINBURG. TO THE QUESTION OF ATTRIBUTION [PDF]
Вестник Екатеринбургской духовной семинарииThe researchers’ interest in the architectural monument of the Classical era of the 1st quarter of the 19th century, the Holy Trinity Cathedral, which in the past was called the Old Believer prayer house, and later Edinoverie Church of the Life-Giving ...
Natalia N. Vanchugova +1 more
doaj +1 more source
‘Unbounded Visions’: Boulez, Mallarmé and Modern Classicism
, 2004 Pli selon pli is Boulez’s richest encounter with Mallarmé. As a ‘portrait’ of the poet which sets three of his sonnets, it can be associated not only with other composers – Ravel, Debussy – who set Mallarmé, but also with the poet’s own views on music ...
Whittall, A
core +1 more source