Results 71 to 80 of about 3,017 (266)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Anthroponyms in the plays of Catherine II [PDF]
Известия Саратовского университета. Новая серия: Серия Филология, ЖурналистикаNaming characters is an opportunity for a playwright not only to indicate the attitude towards a character, but also to defi ne their role in the system of characters and the plot.
Testova, Nika Romanovna
doaj +1 more source
Who Will Be the History Writers of the COVID-19 Pandemic? [PDF]
J Gen Intern Med, 2022 Bishop R, Tran Plata VT, Jabour SM.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Russian Literary Estate in the Context of Artistic Trends. Classicism and Sentimentalism: Results and Prospects of the 18th Century [PDF]
Два века русской классикиThe article examines the dynamics of the estate topos and estate myth in Russian literature of the 18th century, tracing their evolution from conditional rhetorical to mimetic forms within the context of the preceding (16th–17th centuries) and subsequent
Olga A. Bogdanova
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Catalan Historical ReviewNoucentisme was the name given to the hegemonic cultural trend in Catalonia in the early twentieth century. Although initially the main feature of its artistic version was its aim to represent the new century (called the Nou-cents in Catalan), it soon ...
Francesc Fontbona
doaj
THE NEED FOR STATE IN THE ECONOMY- EPISTEMOLOGICAL APPROACH [PDF]
Annals of the University of Petrosani: Economics, 2010 The aim of this paper is to discuss the need for state in the economy, in an epistemological viewpoint. It presents in a critical manner the ideas on the state of the mercantilism and physiocracy representatives, of the classical and Keynesian economists
ANCA-ŞTEFANIA SAVA
doaj
The Pastoral Pipes: A New Musical Instrument and the Aesthetics of Neo-Classicism
, 2020 Christoph Heyl
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FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source