Results 61 to 70 of about 37,536 (309)

Nietzsche’s transcription of the early European counterfeit [PDF]

open access: yes, 2010
An inter-disciplinary enquiry concerning Europe, Europeans and Europeanity across time, based on proceedings of the 10th world congress of the International Society for the Study of European Ideas convened at the University of Malta.
Haaz, Ignace
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

6. Schiller and Romanticism

open access: yes, 1958
To define romanticism is to attempt something which the romantics themselves insist cannot be done. But we can try to identify and then describe it, first pointing out what it is not. One stable element in romanticism has been its consistent rejection of
Bloom, Robert L.   +6 more
core  

A Connectionist Theory of Phenomenal Experience [PDF]

open access: yes, 1999
When cognitive scientists apply computational theory to the problem of phenomenal consciousness, as many of them have been doing recently, there are two fundamentally distinct approaches available.
O'Brien, Gerard, Opie, Jon
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Sigurd Lewerentz: Church of St Peter, Klippan, 1963–66 [PDF]

open access: yes, 2002
This modest building questions basic assumptions about processes and finishes, about the nature of brickwork and the detailing of window frames – and provides a powerful space for ...
Blundell Jones, P.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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