Results 91 to 100 of about 396,157 (408)
Citation classics in systematic reviews and meta-analyses : who wrote the top 100 most cited articles? [PDF]
, 2013 Background: Systematic reviews of the literature occupy the highest position in currently proposed hierarchies of evidence. The aims of this study were to assess whether citation classics exist in published systematic review and meta-analysis (SRM ...
Clarke, Aileen +4 more
core +6 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Classics Illustrated: Limits of Spacetimes
, 2014 We carefully study the $e \rightarrow m$ and $e \rightarrow 0$ limits of the Reissner-Nordstr\"om spacetime using Geroch's definition of limits of spacetimes. This is implemented by embedding the one-parameter family of spacetimes in anti-de Sitter space,
Bengtsson, Ingemar +2 more
core +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Introduction: The Interpretation of Cultures at Fifty
SociologicaIntroducing the symposium “The Interpretation of Cultures at Fifty,” editors Andrea Cossu and Matteo Bortolini reflect on the dynamics of the iconicization of texts and the paradoxical quality of so-called “classics”: their being present while being ...
Andrea Cossu, Matteo Bortolini
doaj +1 more source
Menorah Review (No. 59, Fall, 2003) [PDF]
, 2003 One Deity, Three Gifts -- From the Classics -- Non-Canonical Literature Remembered -- Zion and America -- Weighing the Prospects for Dialogue -- Renewing the Faith of a Diminishing Minority -- From the Classics -- Noteworthy ...
core +1 more source
, 2006 In this JEB Classics paper, Sir James Gray and G. J. Hancock explained how spermatozoa are propelled by flagellar bending waves (Gray and Hancock, 1955). This paper was a lasting success because it provided an easy-to-understand solution to a complicated
Brokaw, Charles J.
core +1 more source