ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad+8 more
wiley +1 more source
Oxford Anthropological Essays - Anthropology and the Classics. Six lectures delivered before the University of Oxford by Arthur J. Evans, Andrew Lang, Gilbert Murray, F. B. Jevons, J. L. Myres, W. Warde Fowler. Edited by R. R. Marett. Oxford: Clarendon Press, 1908. 8vo. Pp. 191. Twenty-two figures. 6s. net. [PDF]
Jack Harrison
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ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang+11 more
wiley +1 more source
Menorah Review (No. 59, Fall, 2003) [PDF]
One Deity, Three Gifts -- From the Classics -- Non-Canonical Literature Remembered -- Zion and America -- Weighing the Prospects for Dialogue -- Renewing the Faith of a Diminishing Minority -- From the Classics -- Noteworthy ...
core +1 more source
Rockwood's Edition of Velleius Paterculus - Velleius Paterculus, Book II., Chapters xli.—cxxxi. By Frank Ernest Rockwood. The Students’ Series of Latin Classics. Leach, Shewell, and Sanborn. $1.25. [PDF]
John C. Rolfe
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In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
Мифология древняя и современная в искусстве и теории искусства
Опираясь на работы философов и искусствоведов российского «течения» 1930-х годов М.А. Лифшица и Д. (Георга) Лукача, автор проводит различие между древней и современной мифологией.
Арсланов, В.Г.
doaj +1 more source
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck+15 more
wiley +1 more source
Menorah Review (No. 77, Summer/Fall, 2012) [PDF]
A Golden Poet of Spain\u27s Golden Age -- Beyond the Second Coming -- Books in Brief: New and Notable -- Cantorial Challenges -- Jewishness in the World: A Chabad Definition -- Moreshet - From the Classics: A 1797 Wedding -- Painful Presence: Jews in ...
core +1 more source