Results 111 to 120 of about 544,465 (411)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Birkhoff Normal Forms in Semi-Classical Inverse Problems [PDF]

open access: yesarXiv, 2002
We apply recent results on semi-classical trace formulae and on Birkhoff normal forms for semi-classical Fourier integral operators to a wide range of semi-classical and high energy spectral inverse problems.
arxiv  

DiBiasie-Sammons receives College of Liberal Arts New Scholar Award in Humanities [PDF]

open access: yes, 2021
Assistant Professor Jacqueline DiBiasie-Sammons has been chosen by the College of Liberal Arts as the 2021 recipient of the Dr. Mike L.
University of Mississippi. Department of Classics
core   +1 more source

Citation Classics in Cone Beam Computed Tomography: The 100 Top-Cited Articles

open access: yesInternational Journal of Dentistry, 2018
Aim The purpose of this study was to identify and characterize the 100 most cited articles on cone beam computed tomography (CBCT). Materials and Methods A comprehensive list of citation classics in CBCT was generated by searching the Scopus database ...
S. Gondivkar   +5 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Semi-Classical Wavefront Set and Fourier Integral Operators [PDF]

open access: yesarXiv, 2004
We define and prove some properties of the semi-classical wavefront set. We also define and study semi-classical Fourier integral operators, of which we give a complete characterization. Lastly, we prove a generalization of the semi-classical Egorov's Theorem to manifolds of unequal dimensions.
arxiv  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

The energy conservation law in classical electrodynamics [PDF]

open access: yesarXiv, 1999
In the framework of the classical Maxwell-Lorentz electrodynamics the energy conservation law is reconsidered.
arxiv  

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