Results 131 to 140 of about 396,157 (408)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Gli Studi Classici E Il Precario Raggiungimento Della Rilevanza [PDF]

, 2012
This talk addresses how the concept of \u27relevance\u27 has tended to be used and abused in our time, and how it has affected public attitudes towards the place of Classics in the academy.
Lefkowitz, Jeremy B.
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

‘Translating’ Classics for Generations Z and Alpha

The Journal of Classics Teaching
This paper presents a public outreach program developed by the Department of Classics at the University of Florida to introduce school-age children to Classics.
Eleni Bozia, Anastasia Pantazopoulou, Anthony J. Smith   +2 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Classical Political Philosophy and the Crisis of Modernity – An alternative to the competition State

Nordicum-Mediterraneum, 2017
The conservative Jewish, German and American philosopher Leo Strauss (1899-1973) proposes an interpretation of the causes of the crisis of modernity and argues that the only way in which we can reestablish social stability is to go back to classical ...
Jacob Dahl Rendtorff
doaj  

Classics revisited: The Josiah Macy, Jr., conferences on gestation

, 1994
Joseph Dancis
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Pia Guldager and Jane Hjar Petersen (eds.), Meetings of cultures in the Black Sea region. Between conflict and coexistence, (Aarhus: Aarhus University Press, 2008)

Nordicum-Mediterraneum, 2011
Book review of Pia Guldiger's and Jane H. Petersen's Meeting of cultures in the Black Sea region. Between conflict and coexistence (Aarhus: Aarhus University Press, 2008).
Carlo Cantaluppi
doaj  

Some Old Movies Become Classics – A Case Study Determining the Scientific Value of ROV Inspection Footage on a Platform on Australia’s North West Shelf [PDF]

, 2018
Paul Thomson, Ashley M. Fowler, Andrew R. Davis, Charitha Pattiaratchi, David J. Booth   +4 more
openalex   +1 more source