Results 71 to 80 of about 2,596,382 (316)

Public attitudes and knowledge about self‐injury: A cross‐sectional web‐based survey of Japanese adults

open access: yesPCN Reports
Aim Nonsuicidal self‐injury is common among adolescents. Dispelling related public misconceptions is essential for creating effective prevention and intervention strategies, as these myths contribute to stigmatization.
Masaru Takahashi   +5 more
doaj   +1 more source

Study on Cost-Effective Performance of Alternative Fuels and Energy Efficiency Measures for Shipping Decarbonization

open access: yesJournal of Marine Science and Engineering
Within the context of global initiatives to address climate change, the shipping industry is facing increasingly intensified pressure to decarbonize.
Huan Tu, Zheyu Liu, Yufeng Zhang
doaj   +1 more source

Reliability analysis of the impact of thickness measurement accuracy on the longitudinal strength assessment of CAP [PDF]

open access: yesE3S Web of Conferences
The reliability analysis of the longitudinal bending strength of ships is conducted using the total probability method, taking into account and analyzing the accuracy error in thickness measurement of transverse section members on existing servicing ...
Zhang Qingyue, Jiang Xueyun
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Typhoon Eye-Induced Misalignment Effects on the Serviceability of Floating Offshore Wind Turbines: Insights Typhoon SOULIK

open access: yesEnergies
The northern Taiwan Strait, characterized by deep waters and high wind energy density, presents significant potential for developing floating offshore wind turbines (FOWTs).
Chun-Yu Yang   +4 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Classification of modern garden rose groups depending on their practical use

open access: yesІнтродукція Рослин, 2004
On the basis of analysis of garden rose existing classifications the unified scheme that is more close to the modern practice is suggested.
О.О. Tkachuk
doaj   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

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