Results 141 to 150 of about 197,388 (314)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Ensemble classifiers for network intrusion detection system [PDF]

open access: yes, 2009
Two of the major challenges in designing anomaly intrusion detection are to maximize detection accuracy and to minimize false alarm rate. In addressing this issue, this paper proposes an ensemble of one-class classifiers where each adopts different ...
Zainal, Anazida   +2 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Choice of handshape and classifier type in placement verbs in American Sign Language

open access: yesOpen Linguistics
This study investigates choice of classifier handshape in the placement verbs MOVE and PUT in American Sign Language (ASL), analyzing data from two deaf ASL signers describing placement events elicited via a semi-structured task.
Frederiksen Anne Therese
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

COMPARATIVE STUDY ON KOREAN AND INDONESIAN NOUN PHRASE INCLUDING NUMERAL CLASSIFIER [PDF]

open access: yes
Speakers from different language might attend reality in different way. Lucy (1992) experimented on English and Yucatec speakers. One of the experiment questions is how they classify a cardboard.
PRIHANTORO, PRIHANTORO
core  

Probabilistic Methods for Object Description and Classification [PDF]

open access: yes, 2006
This thesis extends the utility of probabilistic methods in two diverse domains: multimodal biometrics and machine inspection. The attraction for this approach is that it is easily understood by those using such a system; however the advantages extend ...
Bazin, A. I., Bazin, Alexander Ian
core  

Formal and functional factors in classifier choice: Evidence from American Sign Language and Danish Sign Language

open access: yesOpen Linguistics
Traditionally so-called classifiers in productively formed verbs of motion and location in sign languages are said to reflect the semantic class of the moving or located entity.
Engberg-Pedersen Elisabeth   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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