Results 161 to 170 of about 135,129 (369)
The Clathrin-Mediated Endocytic Pathway Participates in dsRNA-Induced IFN-β Production [PDF]
, 2008 Kiyoharu Itoh +4 more
openalex +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Heterozygous de novo and inherited biallelic pathogenic variants in DNM1 have been reported in association with autosomal dominant (AD) and autosomal recessive (AR) developmental and epileptic encephalopathy, respectively, due to aberrant dynamin function or expression, with each inheritance pattern associated with a different mechanism of ...
Andy Drackley +7 more
wiley +1 more source
Identification of Domain Required for Catalytic Activity of Auxilin in Supporting Clathrin Uncoating by Hsc70 [PDF]
, 2002 Yuchen Ma +5 more
openalex +1 more source
Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs
Advanced NanoBiomed Research, EarlyView.Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna +9 more
wiley +1 more source
Nature CommunicationsClathrin forms a triskelion, or three-legged, network that regulates cellular processes by facilitating cargo internalization and trafficking in eukaryotes.
Lucas A. Defelipe +9 more
doaj +1 more source
Redox‐Activated Probes Enable High‐Contrast Live Imaging of Native Postsynaptic Scaffolds
Angewandte Chemie International Edition, EarlyView.Sylives are modified fluorescent peptides for high‐contrast live imaging of inhibitory (gephyrin) and excitatory (PSD‐95) postsynaptic scaffolds in native neurons. Clean labeling requires low nanomolar probe levels, whereas uptake needs micromolar cell‐penetrating peptide (CPP).
Christiane Huhn +10 more
wiley +1 more source
Clathrin is essential for meiotic spindle function in oocytes [PDF]
, 2010 Jurriaan Hölzenspies +6 more
openalex +1 more source
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source