Results 101 to 110 of about 34,911 (205)

Rational Design, Synthesis, and Biological Evaluation of New Substituted Dihydropyrimidinones as Antibacterial Agents and β‐Lactamase Inhibitors

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Novel 1,6‐dihydropyrimidinones act as antibacterial agents and beta‐lactamase inhibitors. Compounds 3d, 3i, and 7b demonstrated enhanced beta‐lactamase inhibition relative to the standard reference, clavulanic acid, demonstrating significant potentiation effects to restore antibiotic efficacy and combat resistant bacterial strains. ABSTRACT A series of
Ahmed M. Soliman, Heba Abdelrasheed Allam, Walaa R. Mahmoud, Bassem H. Naguib   +3 more
wiley   +1 more source

Hybrid Funnel Technique Reduces Marginal Bone Loss Versus Conventional Drilling: A 3‐Year, Prospective, Non‐randomized, Controlled Clinical Trial

Clinical Implant Dentistry and Related Research, Volume 28, Issue 4, August 2026.
ABSTRACT Purpose This study aimed to compare marginal bone loss (MBL) associated with Hybrid Funnel Technique (HFT) and conventional drill osteotomy for implant site preparation when bioactive implants are used, testing the null hypothesis that no significant differences occur at 1‐ and 3 years.
Luigi Canullo, Yaniv Mayer, Federica Mattalia, Iole D'Urso, Filiberto Mastrangelo, Vito Carlo Alberto Caponio   +5 more
wiley   +1 more source

The role of oral amoxicillin/clavulanic acid in the treatment of osteomyelitis: a systematic review. [PDF]

Eur J Trauma Emerg Surg
Ercolin ESG, Bäthis H, Marche B, Bouillon B, Otchwemah R.   +4 more
europepmc   +1 more source

Beyond Clavulanic Acid biosynthesis: Exploring the broad regulatory impact of BldD in Streptomyces clavuligerus ATCC 27064. [PDF]

PLoS One
Patiño LF, Caicedo-Montoya C, Ríos-Estepa R.   +2 more
europepmc   +1 more source

Clinical Outcomes and Real-World Effectiveness of Amoxicillin-Clavulanic Acid Across Indian Healthcare Settings: A Retrospective Multicenter Study. [PDF]

Cureus
Raju A, Kakar A, Bhagat DK, Behera SK, Pathak R, Pal S.   +5 more
europepmc   +1 more source

Integrated genomic-transcriptomic analysis of clavulanic acid production in differentially productive Streptomyces clavuligerus strains. [PDF]

Sci Rep
Gong J, Yi JS, An S, Cho HS, Shin CH, Won HJ, Lee N, Lee Y, Cho BK, Noh M, Yoon YJ.   +10 more
europepmc   +1 more source

Clavulanic Acid [PDF]

, 2020
openaire   +1 more source

Phosphate ions modulate enzyme activity and epistatic effects in two clavulanic acid-resistant β-lactamase mutants. [PDF]

Protein Sci
Radojković M, Koene SF, Chikunova A, Florea BI, Natarajan SV, Boyle AL, Ubbink M.   +6 more
europepmc   +1 more source

Transcriptome profiles of Streptomyces clavuligerus strains producing different titers of clavulanic acid. [PDF]

Sci Data, 2023
Gong J, Yi JS, Cho HS, Shin CH, Won HJ, Cho BK, Noh M, Yoon YJ.   +7 more
europepmc   +1 more source

Dynamic metabolic modeling of Streptomyces clavuligerus in complex medium highlights nutrient-dependent metabolic transitions associated with clavulanic acid biosynthesis. [PDF]

PLoS One
Toro-Navarro LF, Pinilla-Mendoza L, Ríos-Estepa R.   +2 more
europepmc   +1 more source