Results 161 to 170 of about 5,976,595 (218)
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On the absorption of clavulanic acid
Biopharmaceutics & Drug Disposition, 1988AbstractIt was not possible to computer fit oral clavulanic acid data using exponential or model equations incorporating a single exponential defining the absorption phase. Using the Loo‐Riegelman method three phases of the absorption process became apparent, an initial slow phase, a more rapid phase and a final slow phase, contributing approximately ...
G D, Allen, P E, Coates, B E, Davies
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Clavulanic acid improves ethanol withdrawal symptoms in rats
Iranian Journal of Basic Medical Sciences, 2020Objective(s): Ethanol withdrawal following chronic use, is an important challenge clinically. In this study, the effect of clavulanic acid was evaluated on the symptoms of ethanol withdrawal in rats.
Ehsan Mohebbi +4 more
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International Journal of Oral & Maxillofacial Surgery, 2019
The objectives of this systematic review were to investigate the efficacy of amoxicillin/amoxicillin-clavulanic acid for reducing the risk of postoperative infection after third molar surgery and to evaluate the adverse outcomes in these patients, as ...
R. Menon +4 more
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The objectives of this systematic review were to investigate the efficacy of amoxicillin/amoxicillin-clavulanic acid for reducing the risk of postoperative infection after third molar surgery and to evaluate the adverse outcomes in these patients, as ...
R. Menon +4 more
semanticscholar +1 more source
Polarographic determination of clavulanic acid
Journal of Pharmaceutical and Biomedical Analysis, 1991A method is proposed for the determination of clavulanic acid by differential pulse polarography. The electroactive product was obtained by hydrolysis in sulphuric medium. It shows a reduction peak, that can be used analytically, at -0.75 V (vs SCE).
C, González Pérez +2 more
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The disposition of clavulanic acid in man
Xenobiotica, 1986Following oral administration of potassium 14C-clavulanate to four human subjects, at least 73% of the radioactive dose was absorbed. The mean absolute bioavailability was 64%. Absorption was rapid with peak plasma concentrations of radioactivity and clavulanic acid (2-6 micrograms/ml) occurring between 45 min and three hours after dosing.
G C, Bolton +4 more
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Biochemistry and Action of Clavulanic Acid
Scottish Medical Journal, 1982The destruction of amoxycillin by β-lactamase action represents an important mechanism of bacterial resistance to the drug. Data is presented to illustrate that clavulanic acid used in the form of its potassium salt inhibits the amoxycillin destroying action of many different types of β-lactamase for example: the staphylococcal enzyme, the clinically ...
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