Results 111 to 120 of about 347,870 (327)

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

open access: yesAdvanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen   +7 more
wiley   +1 more source

The School Lunch [PDF]

open access: yes, 1921
Exact date of bulletin unknown.PDF pages ...

core  

Behavior‐ and Cell Type‐Specific Cortico‐Striatal Decoupling in a Parkinson's Disease‐Like Mouse Model

open access: yesAdvanced Science, EarlyView.
Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao   +4 more
wiley   +1 more source

Inclusion of mussel meal in diets to growing/finishing pigs [PDF]

open access: yes, 2013
This study showed that inclusion of mussel meal in diets to growing/finishing pigs yielded growth rate similar to those obtained with a conventional diet, whereas feed conversion ratio was higher.
Andersson, K.   +2 more
core  

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

open access: yesAdvanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang   +27 more
wiley   +1 more source

Review: Analysis of the process and drivers for cellular meat production

open access: yesAnimal, 2019
Cell-based meat, also called ‘clean’, lab, synthetic or in vitro meat, has attracted much media interest recently. Consumer demand for cellular meat production derives principally from concerns over environment and animal welfare, while secondary ...
R.D. Warner
doaj   +1 more source

Author response for "High Pressure‐based Hurdle Interventions for Raw and Processed Meat: A Clean Label Prospective"

open access: gold, 2021
Ume Roobab   +5 more
openalex   +1 more source

Intelligent Stain‐Free Histology on Structural Colorimetric Nanocavities

open access: yesAdvanced Science, EarlyView.
Chen and Gan et al. introduce a label‐free imaging platform using inexpensive Nanocavity‐on‐Silicon (NOS) slides. These slides transform subtle tissue variations into vivid structural colors, enabling high‐contrast histological imaging under a regular optical microscope. This stain‐free approach reveals morphological details comparable to traditional H&
Qizhe Chen   +18 more
wiley   +1 more source

Clean label extraction of bioactive compounds from Chenopodium album and their role in the characterization and stability of ostrich meat

open access: yesFrontiers in Sustainable Food Systems
The demand for clean-label products continues to rise, as consumers increasingly prioritize natural and transparent ingredient lists. Natural substances are generally deemed safe for consumption by consumers.
Muhammad Zubair Khalid   +9 more
doaj   +1 more source

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