Results 41 to 50 of about 1,796,649 (339)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The influence of cyclic loading-unloading rates on the uniaxial mechanical anisotropy of coal
Scientific ReportsIn this study, the influence of the loading-unloading rate on the uniaxial mechanical anisotropy of coal was investigated via uniaxial compressive tests, acoustic emission (AE) monitoring, digital image correlation (DIC), and a series of coal specimens ...
Duo Xu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Handbook of Florida Water Regulation: Clean Water Act
EDIS, 2011 Lost in the maze of statutes, regulations, and potential liabilities that identify the current mass of water protection law? This revised document is part of the Handbook of Florida Water Regulation, which consists of 2-4 page fact sheets that provide ...
Michael T. Olexa +2 more
doaj +5 more sources
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Analysis of the Price of Summary Water Disposal at the Kampung Kasai Derawan Islands Berau District
The Spirit of Society Journal: International Journal of Society Development and EngagementRaw water is water that can be derived from surface water sources, groundwater reservoirs and/or rainwater that is used as raw water for drinking water.
Anang Wahananto +2 more
doaj +1 more source
Local Land Use: Decision Expands Federal Government\u27s Role [PDF]
, 2003 The United States Environmental Protection Agency (EPA), pursuant to its authority under the Clean Water Act, has promulgated regulations creating the Storm Water Management Program.
Nolon, John R.
core +1 more source
Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein
FEBS Open Bio, EarlyView.This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley +1 more source
Case Studies in Chemical and Environmental Engineering, 2022 The general well-being of the human population is highly dependent on the quality, availability, and accessibility to clean water. However, there is a global clean water shortage due to increased industrial activities, population explosion, flooding, and
Abubakar Sadiq Isah +4 more
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source