Results 111 to 120 of about 1,777,378 (290)

Where is clear aligner therapy research heading?

Background and Aim: The aim of this study was tosystematically identify the core themes, research trends, andunderexplored topics in the clear aligner literature by employinga natural language processing-based topic modeling approachusing the BERTopic ...
Yavuz Selim Genç, Nurbanu Moroğlu, Ruşen Erdem, Ahmet Yıldırım, Burkay Moroğlu   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

AI-Driven Quantitative Dental Imaging: A Clinical Framework for Assessing Root Resorption Across Treatment Modalities

Dentistry Journal
Background: Orthodontically induced external root resorption (ERR) may affect long-term tooth stability, requiring a reliable assessment of root length changes.
Atanaz Darvizeh, Saman Fouladi, José Antonio González Sánchez, Guillermo Doria Jaureguizar, Oriol Quevedo, Fernando de la Iglesia Beyme, Funda Goker, Massimo Del Fabbro   +7 more
doaj   +1 more source

Clear Aligners

IP Indian Journal of Orthodontics and Dentofacial Research, 2019
Nausheer Ahmed, Ashwini B.S, Nishat Sidiqha, Shraddha Suryavanshi   +3 more
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

webinar clear aligner in your practice [PDF]

webinar clear aligner in your ...
susi, susi
core  

Evaluation of Mechanical Properties, Color Stability, and Cleaning Efficacy of BioMed Clear Resin‐Based Dental Aligners

Engineering Reports
Clear aligners have gained widespread popularity as a comfortable and aesthetically appealing alternative to traditional braces; however, there is a lack of comprehensive research on the interplay between aligner thickness, color stability, and cleaning ...
Aisyah Safi'ai, Muhammad Imam Ammarullah, Muhammad Hanif Baharuddin, Nur Syafiqah Faidzul Hassan, Muhammad Hanif Ramlee   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The new additive era of orthodontics: 3D-printed aligners and shape memory polymers—the latest trend—and their environmental implications

Journal of Orthodontic Science
The era of printed aligners has just began in the orthodontic field. Orthodontists have become more interested in 3D-printed in-office aligners. Treatment due to this technology can become faster and more efficient.
Amani Alkhamees
doaj   +1 more source