Results 71 to 80 of about 14,551 (299)

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. [PDF]

open access: yes, 2016
The unintended consequences of gene targeting in mouse models have not been thoroughly studied and a more systematic analysis is needed to understand the frequency and characteristics of off-target effects.
Adkisson, Michael   +9 more
core   +4 more sources

Unraveling the Role of Attachments in Clear Aligner Therapy

open access: yes, 2023
The popularity of clear aligner treatments (CATs) have risen multiple folds in the past decade or so due to a demand for an aesthetic appeal and comfort. However, CATs have limitations in achieving certain tooth movements. To enhance predictability, resin attachments have been introduced. This review examines various types of attachments used with CATs,
Aakriti Vashishta   +5 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]

open access: yes, 2018
La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Aligner-driven tooth movement: Biomechanical fundamentals and clinical implications – A review

open access: yesSRM Journal of Research in Dental Sciences
Introduction: Clear aligner therapy (CAT) has become a widely accepted alternative to fixed orthodontic systems, offering esthetic appeal, patient comfort, and digital customization. Despite its popularity, CAT still struggles with issues of efficacy and
Anwesha Garg   +4 more
doaj   +1 more source

Differential Scanning Calorimetry (dsc) Analyses Of Esthetic Nickel-Titanium Wires As-Received And After Clinical Use [PDF]

open access: yes, 2013
Introduction: The demand for esthetic orthodontics has increased rapidly over the past few decades, and much progress has been made in the development of esthetic clear and translucent brackets for labial orthodontics. However, the majority of wires used
Valeri, Nicholas
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

The new additive era of orthodontics: 3D-printed aligners and shape memory polymers—the latest trend—and their environmental implications

open access: yesJournal of Orthodontic Science
The era of printed aligners has just began in the orthodontic field. Orthodontists have become more interested in 3D-printed in-office aligners. Treatment due to this technology can become faster and more efficient.
Amani Alkhamees
doaj   +1 more source

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. [PDF]

open access: yes, 2019
Accelerating cures for children with cancer remains an immediate challenge as a result of extensive oncogenic heterogeneity between and within histologies, distinct molecular mechanisms evolving between diagnosis and relapsed disease, and limited ...
Baxter, Patricia   +68 more
core  

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