Results 51 to 60 of about 43,921 (187)

Seven cases of clear cell papillary renal cell carcinoma and review of literature

Zhongguo aizheng zazhi, 2018
Background and purpose: Clear cell papillary renal cell carcinoma is a rare renal epithelial malignant tumor which was recently discovered. Its biological behavior is inert, and its prognosis is good.
DING Qi, CHANG Yuqing, YUAN Xiaoqi
doaj  

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

Brain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar, Maysa Al‐Hussaini, Vani Santosh, Vaishali Suri, Sung‐Hye Park, Yue‐Shan Piao, Tarik Tihan, Ho‐Keung Ng, Michael Buckland, Rakesh Jalali, Yonehiro Kanemura, Pieter Wesseling, Takashi Komori   +12 more
wiley   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

ALK-rearranged renal cell carcinoma with gains of chromosomes 7 and 17q --- A case report

Urology Case Reports
ALK-rearranged renal cell carcinoma (ALK-RCC) is a rare subtype of RCC. In this report we describe the first ALK-RCC with gains of chromosome 7 and 17q. A 39-year-old male presented with an 11.5 cm renal mass and underwent a left radical nephrectomy. The
Muntha Chaudhari, Hafiz Anas Yahya, Jianming Pei, Gabriel J. DiNatale, Iryna Mahan, James Ryan Mark, Arthur S. Patchefsky, Matthew R. Zibelman, Shuanzeng Wei   +8 more
doaj   +1 more source

Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2016
A multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination.
Jose Ignacio Lopez
doaj   +1 more source

Triple Threat: Three Primary Malignancies Simultaneously Involving Three Genitourinary Organs

Case Reports in Urology, 2023
Statistically, the chance of having concurrent renal cell carcinoma (RCC), urothelial carcinoma of the bladder (UC), and a neuroendocrine tumor (NET) of the renal parenchyma is less than one in a trillion. Herein, we describe an unusual case of a 67-year-
Katharina Mitchell, Reima El Naili, Lakshmikumar Pillai, Eric Mark Lopez, John Riordan, Wallis Marsh, Adam Luchey, Ali Hajiran   +7 more
doaj   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

A case of papillary renal cell carcinoma with para‐aortic lymph node metastasis that was completely resectable after treatment with combination therapy comprising lenvatinib and pembrolizumab and robot‐assisted radical nephrectomy

IJU Case Reports
Introduction Combination therapy comprising immune checkpoint inhibitors and molecular targeted therapies can be effective for metastatic non‐clear cell renal cell carcinoma.
Takayuki Hosoi, Shunsuke Yoshioka, Akari Hiraguri, Yusuke Kirihana, Tomoyuki Koguchi, Makoto Tamaki, Chiharu Irisawa   +6 more
doaj   +1 more source

High PVR protein expression marks clear cell renal cell carcinoma with metastatic spread

Frontiers in Immunology
BackgroundThe poliovirus receptor (PVR) is an emerging therapeutic target currently under clinical investigation in combination with checkpoint inhibitors.
Paola Kučan Brlić, Ema Bellulovich, Mijo Golemac, Ante Jakšić, Dean Markić, Karmela Miklić, Suzana Malić, Emina Babarović, Gordana Đorđević, Vesna Šupak Smolčić, Berislav Lisnić, Pini Tsukerman, Guy Cinamon, Stipan Jonjić, Tihana Lenac Roviš   +14 more
doaj   +1 more source

Case Report: Multifocal biphasic squamoid alveolar renal cell carcinoma [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2016
A multifocal biphasic squamoid alveolar renal cell carcinoma in a 68-year-old man is reported. Four different peripheral tumor nodules were identified on gross examination.
Jose Ignacio Lopez
doaj   +1 more source