Results 111 to 120 of about 250,661 (348)

Renal Clear Cell Carcinoma and Tonsil Metastasis

Case Reports in Otolaryngology, 2013
Renal cell carcinoma is the most common renal tumor in adults. Clear cell carcinoma represents 85% of all histological subtypes. In February 2012 a 72-year-old woman came to our department due to the appearance of massive hemoptysis and pharyngodinia ...
Dario Marcotullio, Giannicola Iannella, Gian Franco Macri, Caterina Marinelli, Melissa Zelli, Giuseppe Magliulo   +5 more
doaj   +1 more source

Gender specific expression of tumor suppressor PKCd versus oncogenic PKCn in renal cell carcinoma [PDF]

, 2003
Tumor incidence for renal cell carcinoma is two-fold higher in males than in females. Members of the protein kinase C (PKC) gene family have been shown to be relevant for carcinogenesis.
Brenner, Walburgis, Färber, Gloria, Hengstler, Jan G., Herget, Thomas, Thüroff, Joachim W., Wiesner, Christoph   +5 more
core  

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Bladder Metastasis from Clear Cell Renal Cell Carcinoma: A Case Report

Caucasian Medical Journal
Kidney cancer is one of the most common urologic cancers. Generally, kidney cancer metastases occur in the liver, lungs, and bones, but we can see rare metastases such as those in the urinary bladder.
İlkin Hamid-Zada, Mammad Khalilov, Özgür Efiloğlu, Asıf Yıldırım   +3 more
doaj   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Molecular Drivers of Chromophobe Renal Cell Carcinoma Revealed Through Genomic Analysis Using AACR Project GENIE

Life
Chromophobe renal cell carcinoma (chRCC) is a distinct subtype of non–clear cell renal cell carcinoma (ncRCC), arising from intercalated cells of the distal nephron collecting ducts.
Abbi Gobel, Grace S. Saglimbeni, Eugene Manu, Nikhita Tandon, Tyson J Morris, Akaash Surendra, Beau Hsia, Peter T. Silberstein, Khalid Bashir, Abubakar Tauseef   +9 more
doaj   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Clear Cell Papillary Renal Cell Carcinoma Incidentally Discovered in a Patient With Normal Renal Function: A Case Report

IJU Case Reports
Introduction Clear cell papillary renal cell carcinoma is a distinct histopathological entity first characterized in patients with end‐stage renal disease.
Toru Inoue, Masahiro Fuse, Satoki Abe, Shinya Sejiyama, Kazuhiro Kawamura, Yuzo Oyama, Tadasuke Ando, Toshitaka Shin   +7 more
doaj   +1 more source

Low Levels of TRIM28-Interacting KRAB-ZNF Genes Associate with Cancer Stemness and Predict Poor Prognosis of Kidney Renal Clear Cell Carcinoma Patients [PDF]

, 2021
Patrycja Czerwińska, Andrzej Maćkiewicz   +1 more
openalex   +1 more source