Results 131 to 140 of about 8,019,599 (294)

Effects of SLC6A3 downregulation on proliferation and migration of SNU-349 cells in renal clear cell carcinoma

Zhongguo aizheng zazhi, 2021
Background and purpose: Solute carrier family 6 member 3 (SLC6A3) is highly expressed in patients with renal clear cell carcinoma. However, the effect of SLC6A3 on the metastasis of renal clear cell carcinoma and its molecular mechanism are still unclear.
王　佳, 艾中中, 周　菁
doaj  

Nuclear Translocation of PFKFB3 Promotes Disuse‐Induced Muscle Atrophy via Scaffolding Nedd4‐Mediated JunB Ubiquitination

Advanced Science, EarlyView.
Disuse‐induced muscle atrophy is driven by a non‐metabolic, nuclear function of the enzyme PFKFB3. Acting as a scaffold, PFKFB3 facilitates Nedd4‐mediated ubiquitination and degradation of the anti‐atrophy transcription factor JunB. Inhibiting this novel PFKFB3–Nedd4–JunB signaling axis stabilizes JunB and alleviates muscle wasting, revealing a highly ...
Mengjun Ma, Yinliang Liu, Wangchang Wu, Biao Yang, Jiahao Zhuang, Haoye Yu, Rujia Mi, Yixuan Lu, Wen Yang, Hanting Yi, Chenglong Yuan, Yinfeng Gu, Hongyu Li   +12 more
wiley   +1 more source

Differentially expressed miRNAs in clear cell renal cell carcinoma compared to benign kidney tissue (n = 38).

, 2012
Tumor: clear cell renal cell carcinoma.
Huiqing Wu (163857), Lihong Weng (163790), Bing Mu (163814), Sharon P. Wilczynski (163833), Hanlin Gao (163838), Sumanta K. Pal (163800), Jeffrey J. Wu (163823), Susan H. Onami (163818), Chao Guo (163795), Nora H. Ruel (163829), Lawrence M. Weiss (163853), Xiwei Wu (136542), Yuping Li (157863), Xuejun Li (133209), Robert A. Figlin (163848), Jennifer M. Jin (163803), Rebecca A. Nelson (163810), Maricela Covarrubias (163843)   +17 more
core   +1 more source

Clear Cell Papillary Renal Cell Carcinoma Incidentally Discovered in a Patient With Normal Renal Function: A Case Report

IJU Case Reports
Introduction Clear cell papillary renal cell carcinoma is a distinct histopathological entity first characterized in patients with end‐stage renal disease.
Toru Inoue, Masahiro Fuse, Satoki Abe, Shinya Sejiyama, Kazuhiro Kawamura, Yuzo Oyama, Tadasuke Ando, Toshitaka Shin   +7 more
doaj   +1 more source

FBP1‐Mediated Compartmentalization of Glycolytic Enzyme Complexes Suppresses PKM2 Function to Ameliorate MASLD Progression

Advanced Science, EarlyView.
In normal hepatocytes, FBP1 forms compartmentalized complexes with PKM2, ENO1, and LDHA independent of its catalytic activity, inhibiting PKM2 activity and restricting excessive glycolysis. During MASLD progression, FBP1 downregulation markedly reduces the abundance of these complexes and releases the “hijacked” glycolytic enzymes, leading to PKM2 ...
Busong Wang, Yiping Tang, Na Li, Xuening Dai, Jing Wu, Bin Xue, Yuxin Chen, Jingzi Zhang, Lingdong Kong, Chaojun Li, Lei Fang   +10 more
wiley   +1 more source

Clear Cell Papillary Renal Cell Carcinoma – A New Emerging Entity [PDF]

, 2012
Clear cell papillary renal cell carcinoma was initially reported in patients with end stage renal disease under name of “end stage renal disease-associated renal cell carcinoma”.
Chen, MD, PhD, Frank, Sule, MD, PhD, Nobert, Xu, MD, PhD, Bo, Kanehira, MD, Kazunori, Sinnott, MD, Michael   +4 more
core  

Case report: A collision tumor of clear cell renal cell carcinoma and clear cell papillary renal cell tumor

Frontiers in Oncology
We report the case of a 51-year-old woman who was initially hospitalized in the respiratory department with cough and fever. Urinary computed tomography (CT) showed two different incidental masses in the right kidney.
Yingsheng Lin, Yingsheng Lin, Jinan Guo, Zaishang Li, Zengqin Liu, Jing Xie, Junxu Liu, Hongtao Jin, Kefeng Xiao   +8 more
doaj   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

Advanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu, Yiyin Rong, Bai Sun, Ziwen Sun, Yifan Wang, Xiaobin Ren, Zelin Cao, Kaikai Gao, Jiawei Yu, Zhenkun Wang, Haoxuan Ma, Jichun Guo, Kai Cao, Mengrun Kang, Songling Wang, Fenggang Ren, Yi Lv, Qiang Lu   +17 more
wiley   +1 more source

Ovarian metastases from renal cell carcinoma: A report of two cases

Fujita Medical Journal
Renal cell carcinoma is a malignant tumor that is prone to distant metastasis, primarily developing in the lungs, bones, lymph nodes, liver, and brain.
Junichi Takagi, Ryoko Ichikawa, Kyohei Takada, Akiko Ohwaki, Mayuko Ito, Yutaka Torii, Hiroyuki Nomura, Haruki Nishizawa   +7 more
doaj   +1 more source