Results 131 to 140 of about 7,424,540 (294)
Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy
Advanced Science, EarlyView.Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan +14 more
wiley +1 more source
IJU Case ReportsIntroduction Clear cell papillary renal cell carcinoma is a distinct histopathological entity first characterized in patients with end‐stage renal disease.
Toru Inoue +7 more
doaj +1 more source
Advanced Science, EarlyView.Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang +9 more
wiley +1 more source
Ovarian metastases from renal cell carcinoma: A report of two cases
Fujita Medical JournalRenal cell carcinoma is a malignant tumor that is prone to distant metastasis, primarily developing in the lungs, bones, lymph nodes, liver, and brain.
Junichi Takagi +7 more
doaj +1 more source
, 2008 Renal cell carcinoma (RCC) is the most common malignancy in adult kidney, and accounts for 3% of malignancies worldwide with increasing incidence. Clear cell RCC (ccRCC) is the major type in RCC.
TANG, SAI-WEN;CHANG, WEN-HSIN;CHAO, YU- WEI;LAI, YEN-HAN;HSU, CHYONG-ING;LIN, WEI-CHOU;WANG, KAO-CHUNG;LAI, MING-KUEN;LIN, JUNG-YAW +1 more
core
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2
Cancer Management and Research, 2019 Fei Liu,1,2 Yuedong Chen,2 Bin Chen,2 Chunxiao Liu,1 Jinchun Xing2 1Department of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of ...
Liu F, Chen Y, Chen B, Liu C, Xing J
doaj
Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics
Advanced Science, EarlyView.DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley +1 more source
The relationship between renal cell carcinoma pathological types and perirenal fat area
BMC CancerIntroduction To explore whether there is a relationship between perirenal fat area (PFA) and the pathological types of renal cell carcinoma (RCC). Methods Two hundred ninety-seven cases of RCC patients were included in our study, which is a retrospective
Xin Leng +7 more
doaj +1 more source
Advanced Science, EarlyView.Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh +22 more
wiley +1 more source