Results 141 to 150 of about 337,050 (372)

Циторедуктивная нефрэктомия в лечении больных с метастатическим светлоклеточным раком почк [PDF]

, 2009
Резюме. Оценена продолжительность жизни пациентов с метастатическим светлоклеточным раком почки, пролеченных в объеме циторедуктивной нефрэктомии, с последующей интерферонотерапией, по сравнению с пациентами, которым удаление почки с опухолью не ...
Григоренко, В.Н., Кондратенко, А.В., Куранов, Ю.Ю., Мрачковский, В.В., Сакало, А.В., Сакало, В.С., Яковлев, П.Г.   +6 more
core  

CT texture analysis: a potential tool for prediction of survival in patients with metastatic clear cell carcinoma treated with sunitinib [PDF]

, 2017
BACKGROUND: To assess CT texture based quantitative imaging biomarkers in the prediction of progression free survival (PFS) and overall survival (OS) in patients with clear cell renal cell carcinoma undergoing treatment with Sunitinib.
Bjarnason, GA, Ganeshan, B, Haider, MA, Khalvati, F, Kiss, A, Vosough, A   +5 more
core   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Pomegranate extract inhibits EMT in clear cell renal cell carcinoma in a NF-κB and JNK dependent manner. [PDF]

, 2015
Objective:Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC) and is characterized by biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene.
Afaq, Ahmed, An, An, An, An, An, Baba, Bosniak, DeSantis, Figlin, Hollingsworth, Koyama, Lamb, Mori, Oya, Oya, Rasheed, Rendon, Rettig, Schubert, Seeram, Semenza, Siegel, Smith, Thomas, Volpe, Wehle, Yang   +28 more
core   +2 more sources

A deep learning framework for automated classification of histopathological kidney whole-slide images

Journal of Pathology Informatics, 2022
Background: Renal cell carcinoma is the most common type of malignant kidney tumor and is responsible for 14,830 deaths per year in the United States. Among the four most common subtypes of renal cell carcinoma, clear cell renal cell carcinoma has the ...
Hisham A. Abdeltawab, Fahmi A. Khalifa, Mohammed A. Ghazal, Liang Cheng, Ayman S. El-Baz, Dibson D. Gondim   +5 more
doaj  

Molecular Genetics of Clear-Cell Renal Cell Carcinoma [PDF]

Journal of Clinical Oncology, 2014
Renal cell carcinoma of clear-cell type (ccRCC) is an enigmatic tumor type, characterized by frequent inactivation of the VHL gene (infrequently mutated in other tumor types), responsiveness to angiogenesis inhibitors, and resistance to both chemotherapy and conventional radiation therapy.
openaire   +2 more sources

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Gene signatures and prognostic values of m6A regulators in clear cell renal cell carcinoma – a retrospective study using TCGA database

Aging, 2019
m6A is the most common form of mRNA modification. However, little is known about its role in clear cell renal cell carcinoma (ccRCC). This study aims to identify gene signatures and prognostic values of m6A regulators in ccRCC.
Jingcheng Zhou, Jiangyi Wang, B. Hong, K. Ma, Haibiao Xie, Lei Li, Kenan Zhang, Bowen Zhou, L. Cai, K. Gong   +9 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Maxillofacial metastasis of genitourinary origin. A report of 3 cases and review of the literature [PDF]

, 2012
Introduction: The maxillofacial region can harbour a wide range of primary tumours, as well as secondary tumours spreading from distant sites. Rare, though nevertheless important among the latter are genitourinary tumours, such as clear cell renal ...
Acosta Moyano, A., Arias Chamorro, Bartolomé, Bermudo Añino, Lucas, Galeas Anaya, Francisco, León Camacho, María De Los Ángeles, Salinas Sánchez, J., Valiente Álvarez, Antonio   +6 more
core   +1 more source